Basic Information
ID: ALA3421227
Type: Binding
Description: Inhibition of human DOT1L using oligo-nucleosome/[3H]-SAM as substrate preincubated for 30 mins followed by substrate addition measured after 120 mins by Morrison plot analysis
Format: BAO_0000357
Organism: Homo sapiens
Target: Histone-lysine N-methyltransferase, H3 lysine-79 specific(ALA1795117)
Document: ALA3414551
Inhibition of human DOT1L using oligo-nucleosome/[3H]-SAM as substrate preincubated for 30 mins followed by substrate addition measured after 120 mins by Morrison plot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3421227
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 539.68 | 2.85 | 2.85 |
| 562.72 | 3.32 | 3.32 |