Basic Information
ID: ALA3423873
Type: Functional
Description: Antagonist activity at human mGluR5 expressed in human embryonic kidney cells assessed as inhibition of L-glutamate-induced calcium release by calcium-5 reagent-based fluorescence assay
Organism: Homo sapiens
Cell type: kidney
Activity Charts
Bioactivity
Activity Types for Assay ALA3423873
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 419.51 | 3.92 | 3.92 |
| 391.46 | 3.10 | 3.10 |
| 437.50 | 4.06 | 4.06 |
| 409.45 | 3.24 | 3.24 |
| 453.96 | 4.57 | 4.57 |
| 425.90 | 3.76 | 3.76 |
| 449.54 | 3.93 | 3.93 |
| 421.48 | 3.11 | 3.11 |
| 405.53 | 4.28 | 4.28 |
| 377.47 | 3.46 | 3.46 |
| 363.45 | 3.15 | 3.15 |
| 423.52 | 4.42 | 4.42 |
| 395.46 | 3.60 | 3.60 |
| 381.44 | 3.29 | 3.29 |
| 439.97 | 4.93 | 4.93 |
| 411.92 | 4.12 | 4.12 |
| 373.48 | 4.43 | 4.43 |
| 391.47 | 4.57 | 4.57 |
| 392.46 | 3.96 | 3.96 |
| 391.47 | 4.57 | 4.57 |
| 387.51 | 4.74 | 4.74 |
| 387.51 | 4.74 | 4.74 |
| 391.47 | 4.57 | 4.57 |
| 409.46 | 4.71 | 4.71 |
| 405.50 | 4.88 | 4.88 |
| 421.50 | 4.58 | 4.58 |
| 391.47 | 4.57 | 4.57 |
| 409.46 | 4.71 | 4.71 |
| 405.50 | 4.88 | 4.88 |
| 421.50 | 4.58 | 4.58 |
| 425.92 | 5.22 | 5.22 |
| 425.92 | 5.22 | 5.22 |
| 421.50 | 4.58 | 4.58 |
| 421.50 | 4.58 | 4.58 |
| 398.49 | 4.30 | 4.30 |
| 428.52 | 4.31 | 4.31 |