Basic Information
ID: ALA3423878
Type: ADME
Description: Inhibition of recombinant human CYP2C19 assessed as remaining activity at 10 uM preincubated for 5 mins followed by substrate and NADP addition measured after 20 mins by fluorescence assay relative to control
Format: BAO_0000357
Organism: Homo sapiens
Target: Cytochrome P450 2C19(ALA3622)
Document: ALA3421577
Inhibition of recombinant human CYP2C19 assessed as remaining activity at 10 uM preincubated for 5 mins followed by substrate and NADP addition measured after 20 mins by fluorescence assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3423878
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 377.47 | 3.46 | 3.46 |
| 391.47 | 4.57 | 4.57 |
| 387.51 | 4.74 | 4.74 |
| 391.47 | 4.57 | 4.57 |
| 421.50 | 4.58 | 4.58 |