Basic Information
ID: ALA3424027
Type: Binding
Description: Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced intracellular Ca2+ level pre-treated 5 mins before capsaicin stimulation by Fluo-4-AM dye based spectrofluorimetry
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3424027
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 302.72 | 3.90 | 3.90 |
| 284.27 | 2.95 | 2.95 |
| 284.27 | 2.95 | 2.95 |
| 298.30 | 3.26 | 3.26 |
| 298.30 | 3.26 | 3.26 |
| 298.30 | 2.74 | 2.74 |
| 298.30 | 2.74 | 2.74 |
| 347.17 | 4.01 | 4.01 |
| 394.17 | 3.85 | 3.85 |
| 302.72 | 3.90 | 3.90 |
| 347.17 | 4.01 | 4.01 |
| 394.17 | 3.85 | 3.85 |
| 396.18 | 3.77 | 3.77 |
| 282.30 | 3.56 | 3.56 |
| 282.30 | 3.56 | 3.56 |
| 310.35 | 4.37 | 4.37 |
| 310.35 | 4.37 | 4.37 |
| 324.38 | 4.54 | 4.54 |
| 361.38 | 2.62 | 2.62 |