Basic Information
ID: ALA3424221
Type: Binding
Description: Inhibition of mouse 11beta-HSD1 overexpressed in microsomal fraction of HEK293 cells assessed as formation of [3H]-cortisol from [3H]-cortisone by scintillation proximity assay in presence of NADPH
Organism: Mus musculus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3424221
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 470.69 | 6.41 | 6.41 |
| 378.55 | 3.58 | 3.58 |
| 420.59 | 4.15 | 4.15 |
| 406.56 | 3.50 | 3.50 |
| 346.51 | 3.73 | 3.73 |
| 388.55 | 4.30 | 4.30 |