Basic Information
ID: ALA3424998
Type: Functional
Description: Antagonist activity at recombinant human NK3R expressed in CHO cells assessed as inhibition of NKB-induced Ca2+ signaling by aequorin Ca2+ bioluminescence assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA3424998
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 402.43 | 2.63 | 2.63 |
| 323.33 | 2.14 | 2.14 |
| 335.37 | 2.00 | 2.00 |
| 323.33 | 2.14 | 2.14 |
| 335.37 | 2.00 | 2.00 |
| 323.33 | 2.14 | 2.14 |
| 335.37 | 2.00 | 2.00 |
| 381.44 | 3.66 | 3.66 |
| 399.43 | 3.80 | 3.80 |
| 415.88 | 4.32 | 4.32 |
| 411.47 | 3.67 | 3.67 |
| 395.47 | 3.59 | 3.59 |
| 387.47 | 3.72 | 3.72 |
| 385.43 | 3.56 | 3.56 |
| 405.85 | 3.04 | 3.04 |
| 337.36 | 2.70 | 2.70 |
| 337.36 | 2.70 | 2.70 |
| 351.39 | 3.00 | 3.00 |
| 337.36 | 2.44 | 2.44 |
| 337.36 | 2.44 | 2.44 |
| 337.36 | 2.44 | 2.44 |
| 337.36 | 2.44 | 2.44 |
| 391.33 | 3.15 | 3.15 |
| 357.41 | 3.07 | 3.07 |
| 419.49 | 4.42 | 4.42 |
| 415.52 | 4.59 | 4.59 |
| 416.51 | 3.99 | 3.99 |
| 519.60 | 6.29 | 6.29 |
| 421.55 | 4.66 | 4.66 |
| 421.55 | 4.66 | 4.66 |
| 407.52 | 4.09 | 4.09 |
| 475.52 | 5.37 | 5.37 |
| 449.61 | 5.47 | 5.47 |
| 433.54 | 5.00 | 5.00 |
| 421.55 | 4.66 | 4.66 |
| 406.47 | 3.58 | 3.58 |
| 422.54 | 4.05 | 4.05 |