Basic Information
ID: ALA3425139
Type: Binding
Description: Inhibition of recombinant human PFKFB2 using fructose 6 phosphate as substrate assessed as ADP generation after 1 hr by ADP Glo assay
Format: BAO_0000357
Organism: Homo sapiens
Target: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2(ALA3421525)
Document: ALA3421585
Inhibition of recombinant human PFKFB2 using fructose 6 phosphate as substrate assessed as ADP generation after 1 hr by ADP Glo assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3425139
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 415.50 | 4.06 | 4.06 |
| 401.51 | 4.60 | 4.60 |
| 415.54 | 4.63 | 4.63 |
| 418.57 | 5.01 | 5.01 |
| 450.56 | 3.69 | 3.69 |
| 400.53 | 4.45 | 4.45 |
| 402.50 | 4.65 | 4.65 |
| 349.39 | 2.80 | 2.80 |
| 335.37 | 2.32 | 2.32 |
| 351.37 | 1.67 | 1.67 |
| 351.37 | 1.67 | 1.67 |
| 306.33 | 3.37 | 3.37 |
| 321.34 | 2.31 | 2.31 |
| 377.45 | 3.44 | 3.44 |
| 411.47 | 3.83 | 3.83 |
| 406.45 | 1.87 | 1.87 |
| 306.33 | 2.73 | 2.73 |
| 334.38 | 3.22 | 3.22 |
| 348.41 | 3.48 | 3.48 |
| 362.43 | 3.83 | 3.83 |
| 374.44 | 4.02 | 4.02 |
| 374.44 | 4.02 | 4.02 |
| 388.47 | 4.04 | 4.04 |
| 360.42 | 3.63 | 3.63 |
| 388.47 | 4.41 | 4.41 |
| 402.45 | 3.57 | 3.57 |
| 417.47 | 2.74 | 2.74 |
| 417.51 | 3.56 | 3.56 |
| 444.54 | 4.42 | 4.42 |
| 422.49 | 4.98 | 4.98 |
| 491.55 | 4.57 | 4.57 |
| 436.52 | 5.04 | 5.04 |
| 455.52 | 4.65 | 4.65 |
| 403.49 | 4.05 | 4.05 |
| 456.51 | 4.04 | 4.04 |
| 362.39 | 2.65 | 2.65 |
| 401.47 | 4.05 | 4.05 |