Assay Report Card

Basic Information

ID: ALA3425247

Type: ADME

Description: Ratio of unbound plasma concentration for inhibition of luteinizing hormone release in castrated Sprague-Dawley rat at 10 mg/kg, po measured at 45 mins to Ki for rat NK3R by [3H]-SB222200 displacement assay

Organism: Rattus norvegicus

Tissue: Plasma

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
421.554.664.66
433.545.005.00
406.473.583.58
422.544.054.05