Basic Information
ID: ALA3428281
Type: Binding
Description: Inhibition of ITK in TCR stimulated human Jurkat T cells assessed as reduction of PLC-gamma phosphorylation preincubated for 30 mins followed by TCR induction for 2 mins
Organism: Homo sapiens
Cell type: Jurkat
Activity Charts
Bioactivity
Activity Types for Assay ALA3428281
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 349.44 | 3.42 | 3.42 |
| 347.42 | 3.03 | 3.03 |
| 420.56 | 3.91 | 3.91 |
| 455.58 | 3.40 | 3.40 |
| 467.60 | 3.40 | 3.40 |
| 481.62 | 3.79 | 3.79 |
| 481.62 | 3.93 | 3.93 |
| 481.62 | 3.79 | 3.79 |
| 465.62 | 4.12 | 4.12 |
| 441.56 | 3.01 | 3.01 |
| 383.40 | 3.28 | 3.28 |
| 479.61 | 3.40 | 3.40 |
| 515.59 | 3.79 | 3.79 |