Basic Information
ID: ALA3428614
Type: ADME
Description: Total plasma concentration in CD1 mouse assessed as (2R,3R,4R,5R,6R)-5-acetamido-4-amino-2,3-difluoro-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid at 30 mg/kg, po measured at 20 mins by reversed-phase UPLC/MS analysis
Organism: Mus musculus
Strain: CD1
Tissue: Plasma
Activity Charts
Bioactivity
Activity Types for Assay ALA3428614
Cp
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 409.43 | -1.62 | -1.62 |
| 435.40 | -1.61 | -1.61 |
| 435.40 | -1.61 | -1.61 |
| 342.30 | -2.89 | -2.89 |
| 356.32 | -2.50 | -2.50 |
| 370.35 | -2.11 | -2.11 |
| 396.39 | -1.58 | -1.58 |
| 398.40 | -1.33 | -1.33 |
| 424.44 | -0.94 | -0.94 |
| 440.48 | -0.16 | -0.16 |
| 496.59 | 1.40 | 1.40 |
| 452.37 | -0.79 | -0.79 |
| 470.47 | -1.54 | -1.54 |
| 498.52 | -0.76 | -0.76 |
| 413.37 | -3.43 | -3.43 |
| 427.40 | -3.04 | -3.04 |
| 424.42 | -1.26 | -1.26 |
| 556.52 | -0.42 | -0.42 |
| 584.57 | 0.36 | 0.36 |
| 327.28 | -3.58 | -3.58 |
| 371.34 | -3.96 | -3.96 |
| 417.41 | -1.75 | -1.75 |
| 399.35 | -3.78 | -3.78 |
| 442.41 | -1.07 | -1.07 |
| 498.52 | 0.63 | 0.63 |
| 382.36 | -1.09 | -1.09 |
| 410.41 | -0.31 | -0.31 |
| 438.47 | 0.18 | 0.18 |
| 408.40 | -0.56 | -0.56 |
| 368.29 | -1.71 | -1.71 |
| 400.33 | -2.10 | -2.10 |
| 428.39 | -1.32 | -1.32 |
| 456.44 | -0.68 | -0.68 |
| 564.54 | 1.08 | 1.08 |
| 450.33 | -1.47 | -1.47 |
| 478.38 | -0.69 | -0.69 |
| 434.33 | -1.40 | -1.40 |