Basic Information
ID: ALA3429505
Type: Binding
Description: Inhibition of recombinant human soluble COMT using dopamine/SAM as substrate/cofactor preincubated for 2 hrs followed by dopamine/SAM addition after 25 mins by fluorescence polarization assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3429505
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.28 | 2.81 | 2.81 |
| 194.22 | 1.20 | 1.20 |
| 263.30 | 3.21 | 3.21 |
| 277.32 | 3.52 | 3.52 |
| 339.39 | 4.88 | 4.88 |
| 305.38 | 4.33 | 4.33 |
| 307.35 | 3.26 | 3.26 |
| 369.42 | 4.29 | 4.29 |
| 335.40 | 4.04 | 4.04 |
| 335.40 | 3.90 | 3.90 |
| 306.37 | 2.71 | 2.71 |
| 278.31 | 2.82 | 2.82 |
| 307.11 |