Basic Information
ID: ALA3429724
Type: Functional
Description: Inhibition of PARP activity in tumor of immunocompromised mouse xenografted with human MDA-MB-436 cells harboring BRCA1 mutant assessed as incorporation of [3H]NAD in PAR chains in response to nicked DNA at 50 to 100 mg/kg, po measured after 24 hrs
Organism: Homo sapiens
Cell type: MDA-MB-436
Activity Charts
Bioactivity
Activity Types for Assay ALA3429724
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 320.40 | 2.59 | 2.59 |