Basic Information
ID: ALA3429725
Type: Functional
Description: Inhibition of PARP activity in tumor of immunocompromised mouse xenografted with BRCA2-deficient human Capan1 cells assessed as incorporation of [3H]NAD in PAR chains in response to nicked DNA at 50 to 100 mg/kg, po measured after 24 hrs
Organism: Homo sapiens
Cell type: CAPAN-1
Activity Charts
Bioactivity
Activity Types for Assay ALA3429725
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 320.40 | 2.59 | 2.59 |