Basic Information
ID: ALA3429767
Type: Binding
Description: Inhibition of His-tagged human recombinant SIRT1 expressed in Escherichia coli at 20 uM using Cbz-Lys(Ac)-AMC as substrate by fluorescence assay
Format: BAO_0000019
Organism: Homo sapiens
Target: NAD-dependent deacetylase sirtuin 1(ALA4506)
Document: ALA3425433
Inhibition of His-tagged human recombinant SIRT1 expressed in Escherichia coli at 20 uM using Cbz-Lys(Ac)-AMC as substrate by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3429767
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 241.29 | 1.98 | 1.98 |
| 289.77 | 2.90 | 2.90 |
| 275.74 | 2.64 | 2.64 |
| 275.74 | 2.64 | 2.64 |
| 310.18 | 3.29 | 3.29 |
| 322.77 | 3.85 | 3.85 |
| 259.28 | 2.12 | 2.12 |
| 271.32 | 1.99 | 1.99 |
| 309.29 | 3.00 | 3.00 |
| 247.32 | 2.04 | 2.04 |
| 280.33 | 2.46 | 2.46 |
| 328.80 | 3.13 | 3.13 |
| 376.28 | 3.96 | 3.96 |
| 294.36 | 2.47 | 2.47 |
| 297.38 | 3.20 | 3.20 |
| 303.79 | 3.42 | 3.42 |
| 338.24 | 3.92 | 3.92 |
| 348.24 | 3.38 | 3.38 |
| 322.41 | 3.11 | 3.11 |
| 325.44 | 3.83 | 3.83 |
| 351.84 | 4.03 | 4.03 |
| 333.77 | 1.99 | 1.99 |
| 303.79 | 3.37 | 3.37 |
| 337.81 | 3.45 | 3.45 |