Basic Information
ID: ALA3430053
Type: Binding
Description: Positive allosteric modulation of recombinant alpha1beta2gamma2 GABAA receptor (unknown origin) expressed in LTK cells assessed as potentiation of GABA-induced channel current treated for 30 s prior to GABA stimulation for 2s by Q-patch assay
Organism: Homo sapiens
Cell type: LTK
Activity Charts
Bioactivity
Activity Types for Assay ALA3430053
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 318.50 | 4.60 | 4.60 |
| 332.53 | 4.99 | 4.99 |
| 318.50 | 4.60 | 4.60 |
| 384.56 | 4.47 | 4.47 |
| 384.56 | 4.47 | 4.47 |
| 385.55 | 3.87 | 3.87 |
| 385.55 | 3.87 | 3.87 |
| 385.55 | 3.87 | 3.87 |
| 386.54 | 3.26 | 3.26 |
| 386.54 | 3.26 | 3.26 |
| 318.50 | 4.60 | 4.60 |
| 384.56 | 4.47 | 4.47 |
| 384.56 | 4.47 | 4.47 |
| 385.55 | 3.87 | 3.87 |
| 385.55 | 3.87 | 3.87 |
| 385.55 | 3.87 | 3.87 |
| 386.54 | 3.26 | 3.26 |
| 386.54 | 3.26 | 3.26 |
| 438.66 | 5.35 | 5.35 |
| 438.66 | 5.35 | 5.35 |
| 434.62 | 5.63 | 5.63 |
| 434.62 | 5.63 | 5.63 |
| 435.61 | 5.02 | 5.02 |
| 435.61 | 5.02 | 5.02 |
| 435.61 | 5.02 | 5.02 |
| 435.61 | 5.02 | 5.02 |
| 435.61 | 5.02 | 5.02 |
| 435.61 | 5.02 | 5.02 |
| 435.61 | 5.02 | 5.02 |
| 435.61 | 5.02 | 5.02 |