Basic Information
ID: ALA3430831
Type: Binding
Description: Delta TM value showing the stabilisation of PLK4 produced by compound binding
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3430831
Thermal melting change
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 377.44 | 4.68 | 4.68 |
| 270.24 | 2.58 | 2.58 |
| 234.30 | 3.91 | 3.91 |
| 327.34 | 3.22 | 3.22 |
| 412.49 | 3.64 | 3.64 |
| 270.24 | 2.58 | 2.58 |
| 302.24 | 1.99 | 1.99 |
| 414.94 | 3.85 | 3.85 |
| 398.48 | 3.33 | 3.33 |
| 338.39 | 2.65 | 2.65 |
| 298.35 | 1.38 | 1.38 |
| 354.46 | 3.20 | 3.20 |
| 393.44 | 3.41 | 3.41 |
| 331.35 | 4.65 | 4.65 |
| 360.35 | 4.85 | 4.85 |
| 246.31 | 4.49 | 4.49 |
| 309.34 | 3.99 | 3.99 |
| 560.64 | 2.41 | 2.41 |
| 403.92 | 3.82 | 3.82 |
| 314.44 | 3.54 | 3.54 |
| 360.21 | 4.15 | 4.15 |
| 267.28 | 3.05 | 3.05 |
| 291.38 | 1.22 | 1.22 |
| 395.23 | 4.03 | 4.03 |
| 388.26 | 4.93 | 4.93 |
| 467.48 | 3.66 | 3.66 |
| 284.34 | 3.13 | 3.13 |
| 301.78 | 3.48 | 3.48 |
| 328.36 | 3.14 | 3.14 |
| 327.18 | 4.09 | 4.09 |
| 293.28 | 3.24 | 3.24 |
| 466.54 | 4.35 | 4.35 |
| 294.31 | 2.32 | 2.32 |
| 280.28 | 2.64 | 2.64 |
| 446.91 | 4.28 | 4.28 |
| 393.40 | 4.61 | 4.61 |
| 244.25 | 2.68 | 2.68 |
| 267.33 | 3.67 | 3.67 |
| 186.17 | 1.53 | 1.53 |
| 400.48 | 1.82 | 1.82 |
| 346.82 | 2.63 | 2.63 |
| 340.43 | 2.81 | 2.81 |
| 364.78 | 2.69 | 2.69 |
| 310.35 | 3.30 | 3.30 |
| 468.56 | 3.51 | 3.51 |
| 330.19 | 3.30 | 3.30 |
| 307.35 | 3.30 | 3.30 |
| 380.50 | 3.12 | 3.12 |
| 368.41 | 3.63 | 3.63 |
| 314.25 | 2.82 | 2.82 |
| 392.15 | -0.77 | -0.77 |
| 346.82 | 5.01 | 5.01 |
| 381.38 | 3.41 | 3.41 |
| 275.26 | 2.11 | 2.11 |
| 210.24 | 2.51 | 2.51 |
| 446.37 | 3.58 | 3.58 |
| 281.31 | 2.78 | 2.78 |
| 402.48 | 2.70 | 2.70 |
| 404.51 | 6.17 | 6.17 |
| 423.54 | 5.31 | 5.31 |
| 356.43 | 2.52 | 2.52 |
| 368.39 | 3.85 | 3.85 |
| 297.31 | 3.10 | 3.10 |
| 388.90 | 4.01 | 4.01 |
| 277.28 | 4.42 | 4.42 |
| 333.34 | 4.53 | 4.53 |
| 293.35 | 0.00 | 0.00 |
| 501.05 | 4.68 | 4.68 |
| 372.42 | 2.99 | 2.99 |
| 363.80 | 4.77 | 4.77 |
| 434.71 | 4.01 | 4.01 |
| 301.35 | 4.07 | 4.07 |
| 324.14 | 0.07 | 0.07 |
| 411.47 | 3.41 | 3.41 |
| 389.46 | 4.27 | 4.27 |
| 372.46 | 3.94 | 3.94 |
| 220.23 | 2.77 | 2.77 |
| 325.34 | 3.88 | 3.88 |
| 438.53 | 3.81 | 3.81 |
| 400.44 | 4.64 | 4.64 |
| 488.02 | 3.31 | 3.31 |
| 413.40 | 5.33 | 5.33 |
| 413.40 | 5.33 | 5.33 |
| 277.28 | 2.65 | 2.65 |
| 276.26 | 1.85 | 1.85 |
| 319.14 | 0.95 | 0.95 |
| 360.01 | 3.51 | 3.51 |
| 178.14 | 1.20 | 1.20 |
| 324.83 | 2.48 | 2.48 |
| 245.24 | -0.70 | -0.70 |
| 568.10 | 3.99 | 3.99 |
| 356.18 | 3.42 | 3.42 |
| 390.53 | 5.29 | 5.29 |
| 425.45 | 1.77 | 1.77 |
| 408.26 | 4.42 | 4.42 |
| 520.95 | 5.01 | 5.01 |
| 287.41 | 3.33 | 3.33 |
| 335.35 | 4.23 | 4.23 |
| 289.67 | 1.67 | 1.67 |
| 404.84 | 5.20 | 5.20 |
| 343.22 | 3.76 | 3.76 |
| 211.22 | 1.90 | 1.90 |
| 398.22 | 3.51 | 3.51 |
| 403.18 | 3.26 | 3.26 |
| 357.35 | 1.90 | 1.90 |
| 311.34 | 3.21 | 3.21 |
| 473.36 | 4.50 | 4.50 |
| 459.59 | 5.34 | 5.34 |
| 185.19 | 1.09 | 1.09 |
| 489.59 | 5.94 | 5.94 |
| 341.80 | 4.85 | 4.85 |
| 416.87 | 4.62 | 4.62 |
| 365.80 | 4.69 | 4.69 |
| 311.34 | 2.38 | 2.38 |
| 68.08 | 0.20 | 0.20 |
| 163.18 | 0.42 | 0.42 |
| 254.24 | 2.18 | 2.18 |
| 318.34 | 3.71 | 3.71 |
| 312.41 | 4.08 | 4.08 |
| 228.25 | 2.10 | 2.10 |
| 396.38 | 1.07 | 1.07 |
| 241.25 | 1.91 | 1.91 |
| 249.34 | 3.06 | 3.06 |
| 387.85 | 3.46 | 3.46 |
| 308.32 | 2.38 | 2.38 |
| 292.36 | 2.08 | 2.08 |
| 346.35 | 3.69 | 3.69 |
| 234.26 | 3.98 | 3.98 |
| 319.43 | 1.92 | 1.92 |
| 327.35 | 2.92 | 2.92 |
| 208.21 | 0.77 | 0.77 |
| 306.75 | 3.14 | 3.14 |
| 398.42 | 3.68 | 3.68 |
| 317.40 | 3.98 | 3.98 |
| 385.90 | 3.49 | 3.49 |
| 366.42 | 2.83 | 2.83 |
| 383.83 | 3.72 | 3.72 |
| 197.15 | 0.93 | 0.93 |
| 354.43 | 3.48 | 3.48 |
| 589.72 | 4.59 | 4.59 |
| 376.77 | 1.71 | 1.71 |
| 460.97 | 3.22 | 3.22 |
| 247.34 | 2.17 | 2.17 |
| 348.36 | 2.98 | 2.98 |
| 371.46 | 2.64 | 2.64 |
| 321.23 | 1.73 | 1.73 |
| 266.34 | 3.03 | 3.03 |
| 553.67 | 3.72 | 3.72 |
| 458.52 | 3.05 | 3.05 |
| 421.81 | 5.65 | 5.65 |
| 353.40 | 2.32 | 2.32 |