Basic Information
ID: ALA3431446
Type: Functional
Description: GSK_TCAKS: pIC50 Trypanosoma cruzi viability assay using beta-GAL activity. This assay was run at single shot at 5uM compound concentration per well. The biological reagents consisted of NIH-3T3 host cells and trypomastigotes parasitic cells; both cell types were set to a 3.3 * 10^5 cells/mL dilution in assay DMEM by means of a CASY cell counter device using a 60um capillary. 6 uL of the mixture were dispensed per well (about 1 * 10^3 host-cells and 1 * 10^3 parasites) with a Multidrop Combi dispenser. Previously, a solution of 1.67 * 10^5 trypomastigotes per mL in assay DMEM had been prepared and 6uL per well dispensed in the allotted control columns that defined 100% inhibition. The 0% inhibition of parasitic growth control was obtained by leaving the assay mixture untreated in its corresponding plate columns. In all wells, the percentage of DMSO never exceeded 0.5%. Plates incubated for four days at 37C, 5% CO2. The substrate used for the assay fluorescence intensity (FLINT) readout was resorufin-beta-D-galactopiranoside (Sigma-Aldrich) at 5uM per well. It was diluted in PBS supplemented with the soft detergent Igepal (Fluka). Upon addition to the plates, the substrate solution was incubated for 4h at room temperature and the signal read with the EnVision microtiter plate reader (Perkin-Elmer) using the corresponding set of filters (excitation/emission at 531/595nm).
Organism: Mus musculus
Strain: Tulahuen
Cell type: NIH3T3
Activity Charts
Bioactivity
Activity Types for Assay ALA3431446
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 308.39 | 2.15 | 2.15 |
| 251.25 | -0.95 | -0.95 |
| 386.40 | 3.01 | 3.01 |
| 296.36 | 3.85 | 3.85 |
| 307.82 | 3.34 | 3.34 |
| 321.31 | 2.85 | 2.85 |
| 363.38 | 2.73 | 2.73 |
| 317.35 | 2.91 | 2.91 |
| 321.72 | 3.90 | 3.90 |
| 330.86 | 4.56 | 4.56 |
| 325.25 | 4.26 | 4.26 |
| 426.54 | 3.48 | 3.48 |
| 285.34 | 3.10 | 3.10 |
| 268.36 | 3.41 | 3.41 |
| 458.53 | 3.20 | 3.20 |
| 268.23 | -2.20 | -2.20 |
| 297.33 | 3.43 | 3.43 |
| 365.27 | 3.26 | 3.26 |
| 387.51 | 5.17 | 5.17 |
| 419.44 | 2.81 | 2.81 |
| 373.37 | 2.08 | 2.08 |
| 349.38 | 2.43 | 2.43 |
| 340.45 | 4.25 | 4.25 |
| 427.51 | 4.13 | 4.13 |
| 210.24 | 2.70 | 2.70 |
| 469.54 | 3.35 | 3.35 |
| 458.57 | 3.26 | 3.26 |
| 352.44 | 3.75 | 3.75 |
| 302.34 | 3.90 | 3.90 |
| 278.36 | 3.90 | 3.90 |
| 332.43 | 3.98 | 3.98 |
| 316.36 | 3.51 | 3.51 |
| 351.39 | 4.21 | 4.21 |
| 428.54 | 3.63 | 3.63 |
| 268.35 | 3.65 | 3.65 |
| 443.53 | 3.53 | 3.53 |
| 446.57 | 3.12 | 3.12 |
| 439.54 | 3.70 | 3.70 |
| 329.81 | 4.19 | 4.19 |
| 329.77 | 3.09 | 3.09 |
| 338.45 | 4.73 | 4.73 |
| 434.93 | 3.59 | 3.59 |
| 332.35 | 1.47 | 1.47 |
| 326.38 | 3.27 | 3.27 |
| 411.46 | 2.24 | 2.24 |
| 464.54 | 3.07 | 3.07 |
| 308.41 | 3.78 | 3.78 |
| 412.95 | 4.11 | 4.11 |
| 385.40 | 2.29 | 2.29 |
| 387.48 | 4.01 | 4.01 |
| 373.46 | 3.25 | 3.25 |
| 369.46 | 3.94 | 3.94 |
| 303.41 | 2.70 | 2.70 |
| 316.36 | 3.51 | 3.51 |
| 299.36 | 2.93 | 2.93 |
| 395.53 | 4.29 | 4.29 |
| 313.38 | 3.97 | 3.97 |
| 364.45 | 3.42 | 3.42 |
| 582.70 | 4.70 | 4.70 |
| 482.40 | 4.82 | 4.82 |
| 442.52 | 3.47 | 3.47 |
| 267.32 | 3.31 | 3.31 |
| 258.20 | 1.23 | 1.23 |
| 291.65 | 2.48 | 2.48 |
| 326.79 | 4.08 | 4.08 |
| 292.34 | 3.43 | 3.43 |
| 357.37 | 2.05 | 2.05 |
| 337.25 | 4.73 | 4.73 |
| 376.71 | 4.33 | 4.33 |
| 685.67 | 4.28 | 4.28 |
| 506.52 | 3.01 | 3.01 |
| 371.47 | 3.34 | 3.34 |
| 296.37 | 2.75 | 2.75 |
| 211.22 | 0.71 | 0.71 |
| 497.35 | 3.87 | 3.87 |
| 474.48 | 3.10 | 3.10 |
| 486.49 | 2.76 | 2.76 |
| 502.54 | 3.62 | 3.62 |
| 504.47 | 2.52 | 2.52 |
| 549.60 | 3.98 | 3.98 |
| 541.53 | 2.68 | 2.68 |
| 544.56 | 3.31 | 3.31 |
| 450.99 | 3.84 | 3.84 |
| 441.39 | 3.74 | 3.74 |
| 456.48 | 0.55 | 0.55 |
| 467.55 | 3.66 | 3.66 |
| 466.54 | 4.27 | 4.27 |
| 393.36 | 1.94 | 1.94 |
| 541.57 | 3.79 | 3.79 |
| 471.58 | 3.67 | 3.67 |
| 418.42 | 4.03 | 4.03 |
| 242.33 | 2.90 | 2.90 |
| 349.39 | 3.92 | 3.92 |
| 387.85 | 2.05 | 2.05 |
| 295.32 | 2.72 | 2.72 |
| 335.43 | 3.95 | 3.95 |
| 325.22 | 4.17 | 4.17 |
| 325.34 | 3.49 | 3.49 |
| 568.59 | 5.31 | 5.31 |
| 450.82 | 4.44 | 4.44 |
| 434.36 | 3.93 | 3.93 |
| 346.35 | 2.39 | 2.39 |
| 302.34 | 3.72 | 3.72 |
| 525.53 | 4.43 | 4.43 |
| 362.46 | 4.01 | 4.01 |
| 388.47 | 2.71 | 2.71 |
| 400.89 | 4.01 | 4.01 |
| 324.30 | 2.75 | 2.75 |
| 321.85 | 2.72 | 2.72 |
| 296.33 | 3.42 | 3.42 |
| 327.45 | 1.28 | 1.28 |
| 425.92 | 3.94 | 3.94 |
| 439.94 | 4.33 | 4.33 |
| 302.40 | 2.79 | 2.79 |
| 409.41 | 4.44 | 4.44 |
| 299.76 | 4.23 | 4.23 |
| 293.37 | 3.61 | 3.61 |
| 485.59 | 4.13 | 4.13 |
| 455.56 | 4.12 | 4.12 |
| 469.59 | 4.51 | 4.51 |
| 259.31 | 3.60 | 3.60 |
| 378.48 | 3.37 | 3.37 |
| 400.55 | 5.21 | 5.21 |
| 339.49 | 2.95 | 2.95 |
| 389.46 | 2.27 | 2.27 |
| 226.19 | 0.15 | 0.15 |
| 409.83 | 5.06 | 5.06 |
| 315.12 | 3.47 | 3.47 |
| 311.13 | 3.33 | 3.33 |
| 388.82 | 2.46 | 2.46 |
| 366.69 | 2.52 | 2.52 |
| 359.41 | 2.95 | 2.95 |
| 403.20 | 2.64 | 2.64 |
| 336.23 | 0.44 | 0.44 |
| 541.48 | 2.43 | 2.43 |
| 339.83 | 4.58 | 4.58 |
| 285.34 | 3.89 | 3.89 |
| 450.49 | 3.40 | 3.40 |
| 341.84 | 4.26 | 4.26 |
| 463.49 | 3.73 | 3.73 |
| 388.43 | 3.99 | 3.99 |
| 326.76 | 3.88 | 3.88 |
| 341.19 | 3.98 | 3.98 |
| 365.45 | 3.94 | 3.94 |
| 402.51 | 3.87 | 3.87 |
| 381.44 | 2.69 | 2.69 |
| 459.55 | 3.38 | 3.38 |
| 307.14 | 4.39 | 4.39 |
| 392.88 | 3.35 | 3.35 |
| 326.14 | 4.55 | 4.55 |
| 605.52 | 2.99 | 2.99 |
| 642.55 | 4.32 | 4.32 |
| 464.49 | 4.68 | 4.68 |
| 413.40 | 4.40 | 4.40 |
| 366.81 | 3.69 | 3.69 |
| 361.38 | 3.97 | 3.97 |
| 373.41 | 3.55 | 3.55 |
| 634.56 | 4.07 | 4.07 |
| 396.42 | 3.51 | 3.51 |
| 320.44 | 3.58 | 3.58 |
| 309.71 | 2.26 | 2.26 |
| 484.95 | 5.11 | 5.11 |
| 331.42 | 1.72 | 1.72 |
| 379.44 | 4.34 | 4.34 |
| 310.33 | 3.45 | 3.45 |
| 375.43 | 4.30 | 4.30 |
| 329.36 | 3.72 | 3.72 |
| 396.83 | 4.25 | 4.25 |
| 387.46 | 3.51 | 3.51 |
| 355.46 | 4.11 | 4.11 |
| 461.52 | 2.78 | 2.78 |
| 432.48 | 4.67 | 4.67 |
| 388.43 | 3.70 | 3.70 |
| 497.62 | 3.94 | 3.94 |
| 403.49 | 3.67 | 3.67 |
| 415.50 | 3.83 | 3.83 |
| 309.39 | 3.18 | 3.18 |
| 479.97 | 2.81 | 2.81 |
| 469.56 | 3.42 | 3.42 |
| 260.36 | 3.69 | 3.69 |
| 382.49 | 4.02 | 4.02 |
| 395.37 | 3.01 | 3.01 |
| 468.47 | 3.98 | 3.98 |
| 333.40 | 3.12 | 3.12 |
| 291.36 | 3.71 | 3.71 |
| 321.38 | 3.72 | 3.72 |
| 361.45 | 3.63 | 3.63 |
| 361.45 | 3.55 | 3.55 |
| 377.45 | 3.25 | 3.25 |
| 572.43 | 2.26 | 2.26 |
| 1242.53 | 1.95 | 1.95 |
| 306.41 | 3.65 | 3.65 |
| 588.46 | 3.82 | 3.82 |
| 437.58 | 4.56 | 4.56 |
| 409.87 | 2.86 | 2.86 |
| 340.38 | 1.78 | 1.78 |
| 354.41 | 2.17 | 2.17 |
| 294.35 | 1.93 | 1.93 |
| 324.38 | 1.94 | 1.94 |
| 338.41 | 2.33 | 2.33 |
| 312.34 | 2.07 | 2.07 |
| 371.44 | 3.04 | 3.04 |
| 337.41 | 2.44 | 2.44 |
| 320.43 | 4.04 | 4.04 |
| 495.45 | 3.89 | 3.89 |
| 351.28 | 4.99 | 4.99 |
| 288.31 | 2.66 | 2.66 |
| 419.48 | 3.01 | 3.01 |
| 322.37 | 3.16 | 3.16 |
| 368.46 | 3.34 | 3.34 |
| 441.32 | 0.65 | 0.65 |
| 387.78 | 3.14 | 3.14 |
| 399.50 | 3.87 | 3.87 |
| 471.61 | 3.03 | 3.03 |
| 430.57 | 2.42 | 2.42 |
| 478.98 | 4.33 | 4.33 |
| 502.04 | 3.11 | 3.11 |
| 476.02 | 4.14 | 4.14 |
| 416.48 | 3.72 | 3.72 |
| 573.56 | 2.91 | 2.91 |
| 365.43 | 4.79 | 4.79 |
| 313.79 | 3.53 | 3.53 |
| 325.80 | 3.50 | 3.50 |
| 431.44 | 4.77 | 4.77 |
| 376.46 | 3.93 | 3.93 |
| 493.59 | 4.95 | 4.95 |
| 489.40 | 3.54 | 3.54 |
| 478.04 | 4.40 | 4.40 |
| 492.05 | 3.06 | 3.06 |
| 463.58 | 4.23 | 4.23 |
| 359.39 | 2.13 | 2.13 |
| 316.21 | 4.06 | 4.06 |
| 317.35 | 2.82 | 2.82 |
| 300.31 | 1.88 | 1.88 |
| 422.92 | 3.36 | 3.36 |
| 356.77 | 3.21 | 3.21 |
| 337.38 | 3.25 | 3.25 |
| 340.31 | 2.70 | 2.70 |
| 489.90 | 4.18 | 4.18 |
| 320.39 | 3.20 | 3.20 |
| 326.42 | 2.10 | 2.10 |
| 426.52 | 3.67 | 3.67 |
| 458.54 | 2.16 | 2.16 |
| 309.37 | 3.44 | 3.44 |
| 294.38 | 2.43 | 2.43 |
| 410.83 | 3.36 | 3.36 |
| 376.26 | 3.43 | 3.43 |
| 297.33 | 3.38 | 3.38 |
| 327.82 | 4.28 | 4.28 |
| 429.53 | 2.96 | 2.96 |
| 387.49 | 3.19 | 3.19 |
| 474.52 | 2.99 | 2.99 |
| 443.32 | 3.91 | 3.91 |
| 318.32 | 1.74 | 1.74 |
| 454.52 | 3.45 | 3.45 |
| 344.41 | 4.95 | 4.95 |
| 366.42 | 2.95 | 2.95 |
| 464.55 | 3.16 | 3.16 |
| 358.24 | 3.64 | 3.64 |
| 458.92 | 3.09 | 3.09 |
| 444.58 | 3.74 | 3.74 |
| 264.33 | 3.23 | 3.23 |
| 379.44 | 3.88 | 3.88 |
| 424.91 | 3.66 | 3.66 |
| 349.44 | 2.66 | 2.66 |
| 364.24 | 3.09 | 3.09 |
| 343.37 | 1.93 | 1.93 |
| 360.85 | 1.74 | 1.74 |
| 692.56 | 3.57 | 3.57 |
| 545.53 | 4.24 | 4.24 |
| 516.56 | 4.20 | 4.20 |
| 377.40 | 3.29 | 3.29 |
| 311.38 | 3.46 | 3.46 |
| 374.40 | 3.13 | 3.13 |
| 388.27 | 3.78 | 3.78 |
| 328.44 | 3.05 | 3.05 |
| 342.40 | 4.24 | 4.24 |
| 364.49 | 3.72 | 3.72 |
| 410.39 | 3.81 | 3.81 |
| 550.49 | 4.00 | 4.00 |
| 419.51 | 3.71 | 3.71 |
| 495.60 | 3.82 | 3.82 |
| 350.43 | 3.55 | 3.55 |
| 302.41 | 2.65 | 2.65 |
| 329.57 | 4.19 | 4.19 |
| 540.54 | 2.73 | 2.73 |
| 368.46 | 3.48 | 3.48 |
| 396.42 | 2.99 | 2.99 |
| 440.93 | 2.95 | 2.95 |
| 464.52 | 3.61 | 3.61 |
| 442.57 | 3.33 | 3.33 |
| 523.47 | 2.22 | 2.22 |
| 383.86 | 3.68 | 3.68 |
| 303.79 | 3.23 | 3.23 |
| 465.56 | 3.43 | 3.43 |
| 468.56 | 4.29 | 4.29 |
| 383.45 | 4.21 | 4.21 |
| 467.59 | 4.19 | 4.19 |
| 394.52 | 4.57 | 4.57 |
| 457.55 | 2.31 | 2.31 |
| 473.62 | 4.18 | 4.18 |
| 435.50 | 3.78 | 3.78 |
| 466.61 | 4.46 | 4.46 |
| 269.30 | 2.68 | 2.68 |
| 401.65 | 4.02 | 4.02 |
| 432.51 | 4.27 | 4.27 |
| 375.45 | 3.05 | 3.05 |
| 414.47 | 2.35 | 2.35 |
| 419.40 | 4.82 | 4.82 |
| 369.45 | 2.41 | 2.41 |
| 372.45 | 4.08 | 4.08 |
| 372.45 | 4.08 | 4.08 |
| 412.54 | 4.73 | 4.73 |
| 588.98 | 3.89 | 3.89 |
| 404.43 | 3.09 | 3.09 |
| 417.43 | 2.19 | 2.19 |
| 277.29 | 2.69 | 2.69 |
| 603.01 | 3.90 | 3.90 |
| 415.48 | 1.91 | 1.91 |
| 300.38 | 3.93 | 3.93 |
| 348.43 | 4.71 | 4.71 |
| 656.56 | 4.66 | 4.66 |
| 406.47 | 3.74 | 3.74 |
| 369.47 | 2.62 | 2.62 |
| 358.40 | 3.12 | 3.12 |
| 496.88 | 3.48 | 3.48 |
| 356.43 | 2.72 | 2.72 |
| 419.51 | 4.30 | 4.30 |
| 422.50 | 4.60 | 4.60 |
| 284.37 | 2.73 | 2.73 |
| 327.39 | 1.58 | 1.58 |
| 487.36 | 2.06 | 2.06 |
| 424.27 | 2.94 | 2.94 |
| 406.47 | 3.76 | 3.76 |
| 379.82 | 2.83 | 2.83 |
| 436.31 | 2.81 | 2.81 |
| 437.47 | 2.73 | 2.73 |
| 395.48 | 2.77 | 2.77 |
| 335.41 | 2.17 | 2.17 |
| 484.95 | 0.95 | 0.95 |
| 407.27 | 2.19 | 2.19 |
| 297.38 | 3.75 | 3.75 |
| 464.52 | 5.55 | 5.55 |
| 406.53 | 4.37 | 4.37 |
| 483.39 | 2.35 | 2.35 |
| 381.46 | 4.32 | 4.32 |
| 418.30 | 2.94 | 2.94 |
| 573.57 | 2.30 | 2.30 |
| 435.94 | 2.15 | 2.15 |
| 475.62 | 3.78 | 3.78 |
| 495.48 | 2.45 | 2.45 |
| 810.62 | 2.88 | 2.88 |
| 376.85 | 2.13 | 2.13 |
| 472.56 | 5.15 | 5.15 |
| 381.44 | 3.68 | 3.68 |
| 499.49 | 4.49 | 4.49 |
| 359.43 | 2.02 | 2.02 |
| 437.55 | 4.30 | 4.30 |
| 383.28 | 2.14 | 2.14 |
| 365.43 | 3.26 | 3.26 |
| 232.24 | 2.10 | 2.10 |
| 388.52 | 3.19 | 3.19 |
| 411.46 | 3.26 | 3.26 |
| 322.37 | 1.69 | 1.69 |
| 380.83 | 4.27 | 4.27 |
| 268.28 | 2.05 | 2.05 |
| 407.89 | 2.57 | 2.57 |
| 393.86 | 2.26 | 2.26 |
| 422.50 | 2.42 | 2.42 |
| 374.41 | 2.27 | 2.27 |
| 335.82 | 3.64 | 3.64 |
| 378.48 | 3.45 | 3.45 |
| 357.42 | 2.91 | 2.91 |
| 400.91 | 2.53 | 2.53 |
| 387.23 | 3.27 | 3.27 |
| 524.54 | 4.11 | 4.11 |
| 459.38 | 3.33 | 3.33 |
| 327.37 | 3.55 | 3.55 |
| 348.36 | 3.18 | 3.18 |
| 602.04 | 4.36 | 4.36 |
| 343.82 | 3.14 | 3.14 |
| 284.34 | 3.42 | 3.42 |
| 213.22 | 1.40 | 1.40 |
| 342.47 | 3.53 | 3.53 |
| 221.69 | 3.10 | 3.10 |
| 294.40 | 3.52 | 3.52 |
| 335.45 | 3.22 | 3.22 |
| 411.40 | 3.18 | 3.18 |
| 289.77 | 2.75 | 2.75 |
| 303.36 | 2.70 | 2.70 |
| 353.45 | 3.14 | 3.14 |
| 357.85 | 2.02 | 2.02 |
| 336.83 | 1.68 | 1.68 |
| 318.75 | 2.78 | 2.78 |
| 342.42 | 3.52 | 3.52 |
| 318.76 | 1.80 | 1.80 |
| 424.03 | 3.63 | 3.63 |
| 429.50 | 4.89 | 4.89 |
| 453.97 | 3.29 | 3.29 |
| 380.85 | 1.95 | 1.95 |
| 353.45 | 4.03 | 4.03 |
| 358.85 | 4.05 | 4.05 |
| 338.41 | 3.69 | 3.69 |
| 350.45 | 4.33 | 4.33 |
| 331.40 | 1.09 | 1.09 |
| 346.45 | 3.81 | 3.81 |
| 412.90 | 4.56 | 4.56 |
| 353.45 | 3.06 | 3.06 |
| 354.39 | 3.33 | 3.33 |
| 304.36 | 2.99 | 2.99 |
| 304.36 | 2.99 | 2.99 |
| 458.54 | 4.22 | 4.22 |
| 324.34 | 1.97 | 1.97 |
| 509.47 | 3.82 | 3.82 |
| 392.85 | 3.45 | 3.45 |
| 246.70 | 3.30 | 3.30 |
| 386.76 | 3.86 | 3.86 |
| 379.36 | 4.42 | 4.42 |
| 335.38 | 1.72 | 1.72 |
| 281.22 | 2.41 | 2.41 |
| 416.41 | 3.52 | 3.52 |
| 392.42 | 2.92 | 2.92 |
| 227.27 | 2.65 | 2.65 |
| 228.28 | 2.60 | 2.60 |
| 459.53 | 3.53 | 3.53 |
| 469.37 | 2.86 | 2.86 |
| 350.42 | 3.48 | 3.48 |
| 346.43 | 3.58 | 3.58 |
| 334.37 | 2.99 | 2.99 |
| 350.42 | 3.87 | 3.87 |
| 297.40 | 3.11 | 3.11 |
| 355.44 | 2.70 | 2.70 |
| 355.44 | 2.70 | 2.70 |
| 341.42 | 2.27 | 2.27 |
| 355.44 | 2.66 | 2.66 |
| 337.41 | 2.83 | 2.83 |
| 328.37 | 1.82 | 1.82 |
| 282.31 | 1.32 | 1.32 |
| 295.35 | 2.56 | 2.56 |
| 346.89 | 4.04 | 4.04 |
| 309.42 | 2.98 | 2.98 |
| 328.20 | 2.77 | 2.77 |
| 343.77 | 2.71 | 2.71 |
| 327.43 | 3.13 | 3.13 |
| 319.37 | 2.54 | 2.54 |
| 442.48 | 3.42 | 3.42 |
| 365.52 | 3.92 | 3.92 |
| 449.43 | 3.38 | 3.38 |
| 449.43 | 3.38 | 3.38 |
| 433.43 | 3.68 | 3.68 |
| 453.85 | 4.02 | 4.02 |
| 252.28 | 2.16 | 2.16 |
| 330.39 | 3.58 | 3.58 |
| 305.34 | 2.61 | 2.61 |
| 322.37 | 1.94 | 1.94 |
| 381.48 | 4.79 | 4.79 |
| 351.41 | 2.52 | 2.52 |
| 326.40 | 1.90 | 1.90 |
| 604.61 | 3.33 | 3.33 |
| 588.61 | 3.63 | 3.63 |
| 343.43 | 4.02 | 4.02 |
| 577.63 | 4.06 | 4.06 |
| 326.42 | 3.47 | 3.47 |
| 340.46 | 3.65 | 3.65 |
| 325.46 | 3.03 | 3.03 |
| 308.43 | 4.21 | 4.21 |
| 349.41 | 3.54 | 3.54 |
| 331.39 | 3.61 | 3.61 |
| 338.24 | 3.50 | 3.50 |
| 518.97 | 2.95 | 2.95 |
| 290.37 | 4.05 | 4.05 |
| 525.02 | 3.13 | 3.13 |
| 400.53 | 4.53 | 4.53 |
| 545.61 | 4.78 | 4.78 |
| 488.01 | 2.90 | 2.90 |
| 488.01 | 2.90 | 2.90 |
| 482.99 | 4.72 | 4.72 |
| 337.40 | 3.58 | 3.58 |
| 311.39 | 3.66 | 3.66 |
| 496.62 | 3.61 | 3.61 |
| 421.24 | 2.97 | 2.97 |
| 318.69 | 3.69 | 3.69 |
| 349.37 | 4.17 | 4.17 |
| 361.40 | 4.04 | 4.04 |
| 608.67 | 4.43 | 4.43 |
| 353.40 | 3.41 | 3.41 |
| 410.95 | 4.18 | 4.18 |
| 501.38 | 2.30 | 2.30 |
| 315.80 | 4.49 | 4.49 |
| 369.40 | 3.58 | 3.58 |
| 355.38 | 3.19 | 3.19 |
| 391.43 | 4.05 | 4.05 |
| 461.49 | 4.02 | 4.02 |
| 496.55 | 3.33 | 3.33 |
| 469.63 | 3.47 | 3.47 |
| 507.03 | 2.74 | 2.74 |
| 489.61 | 2.72 | 2.72 |
| 427.55 | 4.42 | 4.42 |
| 241.04 | 2.54 | 2.54 |
| 720.67 | 4.64 | 4.64 |
| 597.63 | 4.41 | 4.41 |
| 433.31 | 3.51 | 3.51 |
| 292.30 | 3.42 | 3.42 |
| 463.59 | 3.46 | 3.46 |
| 518.89 | 5.15 | 5.15 |
| 554.59 | 3.26 | 3.26 |
| 615.59 | 3.32 | 3.32 |
| 356.84 | 3.92 | 3.92 |
| 391.45 | 4.96 | 4.96 |
| 321.34 | 3.89 | 3.89 |
| 359.39 | 3.19 | 3.19 |
| 517.94 | 5.30 | 5.30 |
| 316.36 | 3.64 | 3.64 |
| 482.34 | 4.47 | 4.47 |
| 498.61 | 4.53 | 4.53 |
| 463.41 | 5.31 | 5.31 |
| 477.39 | 5.03 | 5.03 |
| 442.57 | 3.88 | 3.88 |
| 297.32 | 2.07 | 2.07 |
| 292.25 | 2.46 | 2.46 |
| 471.47 | 3.55 | 3.55 |
| 427.46 | 3.82 | 3.82 |
| 329.34 | 2.55 | 2.55 |
| 270.76 | 3.85 | 3.85 |
| 413.48 | 2.95 | 2.95 |
| 341.37 | 1.23 | 1.23 |
| 425.51 | 3.31 | 3.31 |
| 491.49 | 4.37 | 4.37 |
| 469.61 | 2.95 | 2.95 |
| 475.56 | 3.22 | 3.22 |
| 387.48 | 4.01 | 4.01 |
| 437.29 | 3.85 | 3.85 |
| 369.60 | 4.48 | 4.48 |
| 347.40 | 3.90 | 3.90 |
| 419.66 | 4.16 | 4.16 |
| 345.78 | 3.40 | 3.40 |
| 374.87 | 4.22 | 4.22 |
| 387.48 | 4.01 | 4.01 |
| 490.59 | 4.17 | 4.17 |
| 471.97 | 3.88 | 3.88 |
| 426.94 | 4.26 | 4.26 |
| 480.48 | 3.78 | 3.78 |
| 311.41 | 4.02 | 4.02 |
| 270.38 | 3.21 | 3.21 |
| 393.78 | 3.03 | 3.03 |
| 306.82 | 3.72 | 3.72 |
| 437.84 | 2.68 | 2.68 |
| 324.41 | 3.33 | 3.33 |
| 569.06 | 2.07 | 2.07 |
| 231.30 | 1.70 | 1.70 |
| 301.35 | 3.32 | 3.32 |
| 274.66 | 3.91 | 3.91 |
| 227.02 | 2.23 | 2.23 |
| 304.78 | 2.83 | 2.83 |
| 225.32 | 1.85 | 1.85 |
| 419.53 | 4.63 | 4.63 |
| 546.67 | 5.73 | 5.73 |
| 385.77 | 2.71 | 2.71 |
| 446.53 | 4.65 | 4.65 |
| 322.70 | 3.21 | 3.21 |
| 307.31 | 3.18 | 3.18 |
| 418.52 | 3.13 | 3.13 |
| 292.34 | 3.60 | 3.60 |
| 423.97 | 2.79 | 2.79 |
| 407.97 | 3.35 | 3.35 |
| 280.33 | 1.33 | 1.33 |
| 553.44 | 2.99 | 2.99 |
| 384.69 | 3.58 | 3.58 |
| 222.25 | 3.00 | 3.00 |
| 367.39 | 1.58 | 1.58 |
| 366.41 | 2.33 | 2.33 |
| 413.36 | 3.91 | 3.91 |
| 426.90 | 3.34 | 3.34 |
| 344.33 | 2.60 | 2.60 |
| 352.23 | 4.09 | 4.09 |
| 408.96 | 2.15 | 2.15 |
| 545.13 | 4.10 | 4.10 |
| 425.33 | 4.36 | 4.36 |
| 479.27 | 4.25 | 4.25 |
| 372.47 | 4.26 | 4.26 |
| 454.35 | 4.20 | 4.20 |
| 567.47 | 2.56 | 2.56 |
| 279.55 | 2.71 | 2.71 |
| 465.56 | 4.25 | 4.25 |