Assay Report Card

Basic Information

ID: ALA3436041

Type: Functional

Description: ST_JUDE_LEISH: Cytotoxicity against transgenic Leishmania Mexicana promastigotes LmGLUT1 that are glucose transport deficient and complemented with the human glucose transporter GLUT1. Activity is measured by DNA content using SYBR green in vitro

Organism: Leishmania mexicana

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
350.035.945.94
291.403.883.88
512.445.775.77
480.654.944.94
354.465.345.34
367.493.733.73
243.22-2.56-2.56
277.803.643.64
482.374.884.88
368.484.884.88
281.351.041.04
279.393.753.75
288.313.363.36
337.184.124.12
358.835.395.39
265.310.500.50
255.322.642.64
283.383.283.28
379.422.822.82
297.413.673.67
241.302.402.40
283.383.423.42
283.383.073.07
348.412.032.03
245.282.682.68
272.313.663.66
440.465.395.39
325.594.754.75
267.364.264.26
319.454.594.59
275.313.333.33
333.312.842.84
454.463.703.70
516.675.375.37
268.274.024.02
268.353.653.65
339.403.953.95
239.281.931.93
273.332.442.44
231.301.531.53
308.834.194.19
357.394.524.52
367.384.314.31
234.252.492.49
325.804.654.65
436.472.162.16
269.394.074.07
303.364.514.51
333.873.893.89
188.191.131.13
346.403.333.33
270.334.904.90
339.353.313.31
365.874.354.35
302.762.962.96
295.353.043.04
361.234.164.16
283.383.363.36
297.791.271.27
636.908.798.79
650.596.016.01
678.727.017.01
561.542.642.64
379.463.273.27
339.323.533.53
415.415.185.18
469.516.046.04
289.342.952.95
716.198.138.13
290.253.793.79
441.864.824.82
627.596.636.63
631.697.527.52
405.504.804.80
338.284.624.62
359.411.471.47
409.454.904.90
347.263.783.78
476.584.504.50
449.025.855.85
332.364.704.70
471.584.574.57
298.774.954.95
646.846.046.04
444.604.994.99
370.933.363.36
406.964.204.20
603.714.294.29
599.725.425.42
403.444.514.51
407.523.333.33
485.126.566.56
364.451.181.18
353.353.923.92
501.974.694.69
278.313.903.90
407.614.494.49
584.877.187.18
386.433.383.38
370.933.443.44
481.503.333.33
521.934.024.02
328.404.704.70
365.444.464.46
315.384.454.45
589.683.983.98
642.117.297.29
530.694.254.25
548.015.405.40
531.972.342.34
420.516.716.71
368.664.804.80
386.433.323.32
413.354.954.95
464.452.532.53
548.015.405.40
428.382.582.58
502.563.203.20
497.125.905.90
574.696.936.93
323.353.093.09
552.746.456.45
367.283.703.70
249.752.912.91
426.524.394.39
292.394.504.50
442.326.406.40
510.437.687.68
465.266.546.54
303.373.113.11
478.992.992.99
571.687.187.18
383.674.944.94
580.796.546.54
608.858.018.01
608.623.923.92
298.412.922.92
611.645.175.17
393.404.514.51
534.605.215.21
349.263.653.65
476.057.297.29
448.377.157.15
399.453.343.34
521.586.836.83
292.772.612.61
519.954.664.66
468.323.343.34
505.064.064.06
372.425.135.13
435.444.684.68
437.905.865.86
255.322.402.40
314.863.383.38
465.593.983.98
431.566.926.92
563.633.693.69
367.412.532.53
456.985.345.34
397.442.402.40
417.514.324.32
208.651.091.09
701.497.187.18
412.495.475.47
304.380.990.99
590.647.477.47
479.853.903.90
398.515.205.20
497.754.594.59
547.974.204.20
354.474.024.02
476.505.065.06
440.533.523.52
413.534.114.11
338.151.601.60
307.863.703.70
432.364.414.41
583.704.394.39
672.846.486.48
565.983.443.44
380.682.852.85
492.585.335.33
580.516.686.68
285.772.202.20
407.614.344.34
420.685.555.55
359.773.663.66
420.493.683.68
326.402.712.71
484.963.173.17
517.114.944.94
702.867.527.52
500.583.673.67
314.352.672.67
693.768.528.52
397.504.244.24
307.332.942.94
283.383.333.33
509.096.516.51
493.096.456.45
621.637.067.06
458.804.364.36
379.463.353.35
341.445.945.94
574.245.295.29
384.504.034.03
346.434.204.20
570.404.084.08
552.745.755.75
477.614.744.74
346.822.792.79
595.664.474.47
464.962.692.69
710.836.126.12
401.474.484.48
542.354.364.36
508.156.026.02
549.983.743.74
688.737.627.62
350.296.156.15
513.685.745.74
339.404.034.03
505.473.503.50
436.585.225.22
418.594.274.27
484.445.945.94
686.568.178.17
600.046.656.65
319.372.812.81
448.166.016.01
261.414.114.11
385.875.305.30
367.674.124.12
490.525.355.35
350.382.212.21
720.867.057.05
456.514.034.03
377.874.094.09
551.675.055.05
328.174.124.12
468.857.027.02
493.614.004.00
381.824.254.25
524.547.397.39
319.363.473.47
413.014.614.61
384.963.833.83
482.584.564.56
501.033.013.01
665.727.987.98
436.945.755.75
391.494.524.52
343.394.494.49
309.823.803.80
331.424.354.35
495.023.683.68
504.484.114.11
495.667.487.48
337.363.303.30
331.384.314.31
252.322.882.88
636.7110.4510.45
362.524.074.07
491.544.324.32
386.433.383.38
605.521.641.64
360.505.015.01
511.023.083.08
555.206.026.02
552.745.755.75
413.525.595.59
397.543.753.75
316.844.314.31
354.414.464.46
189.221.531.53
312.424.344.34
407.614.344.34
438.904.044.04
326.454.464.46
683.769.779.77
444.757.007.00
688.738.328.32
518.063.943.94
429.323.803.80
533.463.623.62
562.596.696.69
389.554.924.92
458.523.153.15
418.195.565.56
612.796.476.47
420.913.343.34
356.813.383.38
702.867.527.52
268.353.653.65
367.391.581.58
603.50
292.343.423.42
549.054.924.92
560.805.215.21
469.556.116.11
604.844.744.74
362.444.244.24
312.382.612.61
281.282.922.92
289.343.203.20
420.184.454.45
649.806.666.66
379.903.973.97
403.443.383.38
492.612.312.31
608.857.327.32
545.217.317.31
392.823.413.41
558.194.994.99
403.924.794.79
433.595.705.70
307.382.492.49
533.374.744.74
402.114.774.77
688.738.328.32
333.352.532.53
505.412.872.87
636.908.798.79
248.282.742.74
561.584.134.13
556.574.294.29
406.853.723.72
636.908.508.50
478.555.025.02
487.776.436.43
627.596.636.63
496.486.796.79
358.375.165.16
389.803.673.67
507.054.874.87
610.656.286.28
441.334.794.79
306.332.352.35
537.555.635.63
581.225.655.65
523.525.105.10
382.344.304.30
668.908.038.03
382.464.704.70
514.033.723.72
273.241.871.87
579.664.904.90
469.705.105.10
531.105.415.41
363.424.244.24
513.524.354.35
430.525.225.22
430.525.535.53
617.327.907.90
391.304.794.79
591.035.655.65
630.067.297.29
413.483.733.73
360.494.474.47
523.444.004.00
440.894.424.42
594.547.077.07
575.614.524.52
387.494.314.31
290.332.192.19
551.615.925.92
542.486.016.01
400.954.574.57
370.465.305.30
287.404.774.77
453.265.415.41
410.604.934.93
218.261.351.35
554.576.086.08
286.773.263.26
475.382.862.86
475.383.813.81
462.433.683.68
495.505.075.07
555.034.674.67
489.925.545.54
359.224.264.26
495.074.074.07
432.363.283.28
459.936.396.39
503.004.824.82
462.393.363.36
456.985.345.34
480.015.375.37
520.635.325.32
349.534.704.70
589.684.554.55
366.355.455.45
420.474.634.63
462.594.524.52
269.353.113.11
461.614.514.51
515.535.165.16
503.023.513.51
309.323.383.38
519.964.824.82
422.445.335.33
588.573.143.14
688.737.627.62
631.646.206.20
339.446.346.34
322.454.084.08
598.304.434.43
696.958.118.11
419.574.934.93
399.324.914.91
612.796.476.47
341.724.164.16
726.975.875.87
494.503.013.01
439.565.885.88
315.384.454.45
494.563.013.01
447.475.355.35
377.363.793.79
526.515.715.71
587.219.989.98
288.764.004.00
413.014.614.61
427.045.005.00
478.635.015.01
470.447.117.11
298.423.943.94
370.493.803.80
303.393.913.91
496.017.337.33
517.166.536.53
279.353.033.03
447.546.426.42
434.543.953.95
463.974.094.09
494.664.964.96
491.167.477.47
329.382.382.38
340.403.763.76
436.006.456.45
598.237.527.52
668.908.038.03
431.325.345.34
333.403.413.41
459.624.694.69
482.515.345.34
398.984.224.22
464.953.433.43
406.495.555.55
340.794.724.72
348.493.833.83
559.555.715.71
349.314.044.04
357.414.884.88
580.494.364.36
527.197.677.67
429.614.404.40
364.455.255.25
336.273.953.95
442.565.175.17
527.985.555.55
474.394.484.48
684.978.718.71
493.404.644.64
489.146.496.49
488.595.435.43
448.524.304.30
308.815.125.12
397.775.215.21
419.905.045.04
377.874.644.64
289.342.802.80
513.013.823.82
608.525.275.27
398.984.224.22
515.157.637.63
388.524.854.85
458.635.305.30
381.404.704.70
447.584.044.04
432.923.713.71
637.704.134.13
404.473.693.69
480.615.885.88
511.207.347.34
658.856.326.32
580.025.215.21
362.865.435.43
608.857.327.32
367.384.314.31
373.414.504.50
339.825.415.41
367.674.124.12
670.948.328.32
646.846.046.04
632.878.018.01
457.834.304.30
327.703.853.85
324.815.145.14
479.543.313.31
367.535.105.10
679.778.898.89
492.552.792.79
403.315.415.41
380.882.532.53
470.176.646.64
422.324.754.75
501.075.295.29
426.544.884.88
633.566.106.10
516.916.126.12
531.065.525.52
673.435.255.25
512.534.154.15
561.309.179.17
522.454.604.60
557.595.305.30
462.392.982.98
630.708.078.07
266.732.622.62
440.436.596.59
440.554.794.79
589.683.983.98
347.844.634.63
406.853.723.72
422.553.783.78
445.535.145.14
628.087.077.07
545.535.835.83
336.383.913.91
370.423.243.24
456.595.375.37
306.414.444.44
486.025.535.53
463.924.504.50
402.335.255.25
430.904.724.72
268.323.003.00
586.755.635.63
465.627.407.40
280.173.963.96
353.381.401.40
393.492.912.91
356.434.994.99
405.503.623.62
387.496.346.34
496.505.205.20
228.343.173.17
434.495.475.47
283.714.014.01
371.872.832.83
199.252.412.41
298.775.035.03
378.494.124.12
453.335.785.78
468.343.783.78
199.252.982.98
423.433.393.39
274.393.853.85
267.343.053.05
453.558.408.40
265.322.982.98
260.350.940.94
460.546.386.38
326.404.994.99
316.794.004.00
332.514.234.23
427.322.762.76
422.963.073.07
384.313.953.95
380.444.794.79
341.424.764.76
319.433.523.52
554.517.907.90
328.202.532.53
268.144.114.11
445.523.513.51
274.323.413.41
362.433.883.88
419.486.336.33
659.696.646.64
293.323.783.78
345.832.902.90
413.596.796.79
337.435.525.52
359.435.615.61
201.273.203.20
334.383.523.52
357.412.072.07
496.695.565.56
645.206.866.86
346.903.793.79
376.434.974.97
347.844.084.08
318.334.394.39
394.433.543.54
382.872.652.65
484.605.965.96
463.964.654.65
287.374.444.44
287.794.314.31
314.434.754.75
546.607.487.48
335.843.433.43
440.293.003.00
338.284.624.62
335.453.893.89
307.444.534.53
232.713.493.49
371.465.955.95
284.753.923.92
292.514.084.08
334.393.583.58
420.566.036.03
460.564.894.89
362.444.504.50
331.422.602.60
480.595.345.34
391.414.144.14
286.333.963.96
358.393.933.93
301.413.913.91
261.753.903.90
355.444.974.97
420.336.706.70
389.365.795.79
354.815.785.78
348.404.674.67
356.435.575.57
469.015.995.99
592.668.208.20
409.514.624.62
360.893.323.32
451.577.357.35
294.453.503.50
349.863.963.96
396.924.964.96
357.894.754.75
282.552.732.73
579.129.649.64
662.873.603.60
287.321.311.31
268.363.673.67
308.364.284.28
289.344.034.03
290.252.922.92
245.282.272.27
320.404.154.15
480.597.287.28
357.255.455.45
335.323.563.56
309.413.343.34
637.735.505.50
420.513.923.92
308.393.393.39
245.323.603.60
279.343.293.29
312.192.552.55
265.402.822.82
382.255.795.79
657.777.707.70
273.723.533.53
410.431.581.58
500.195.135.13
359.483.733.73
349.224.084.08
274.322.762.76
524.587.527.52
362.273.633.63
621.787.237.23
501.377.047.04
426.596.096.09
631.737.207.20
406.515.015.01
286.764.344.34
357.812.132.13
348.195.215.21
469.313.613.61
305.853.633.63
389.544.174.17
380.364.824.82
559.646.406.40
416.524.174.17
312.412.722.72
390.514.424.42
448.595.015.01
291.823.073.07
254.333.283.28
368.915.095.09
286.204.114.11
282.162.542.54
366.893.953.95
434.565.335.33
293.533.633.63
336.394.034.03
462.625.405.40
432.915.435.43
414.494.734.73
377.914.044.04
417.444.964.96
468.475.095.09
411.965.825.82
293.323.763.76
310.424.854.85
303.794.094.09
436.015.105.10
391.904.484.48
411.634.274.27
360.244.224.22
367.414.094.09
314.473.793.79
458.865.495.49
333.585.435.43
327.434.184.18
363.464.654.65
314.824.554.55
453.583.843.84
395.535.205.20
355.953.723.72
425.964.844.84
458.634.564.56
281.144.294.29
278.714.434.43
400.464.424.42
315.844.994.99
352.795.615.61
425.964.844.84
450.585.355.35
350.855.535.53
315.684.324.32
416.294.164.16
321.803.403.40
383.493.793.79
487.033.593.59
417.984.254.25
308.433.693.69
395.734.134.13
297.242.352.35
279.413.293.29
384.503.673.67
398.465.245.24
401.895.655.65
403.953.863.86
167.120.800.80
265.251.091.09
320.354.214.21
472.474.434.43
480.914.464.46
440.554.764.76
329.843.613.61
309.332.182.18
368.403.793.79
392.422.282.28
468.118.208.20
431.374.604.60
363.894.354.35
254.311.621.62
254.273.093.09
335.833.573.57
393.314.234.23
280.334.004.00
310.383.593.59
358.446.346.34
321.313.813.81
341.330.310.31
490.675.475.47
380.493.693.69
519.985.525.52
487.696.596.59
485.656.656.65
489.525.365.36
420.494.834.83
401.514.704.70
396.485.115.11
492.915.815.81
476.916.116.11
472.455.305.30
317.823.523.52
301.782.522.52
311.394.854.85
491.955.685.68
341.414.864.86
484.606.206.20
405.483.933.93
352.442.432.43
348.314.544.54
465.474.324.32
389.886.116.11
493.575.115.11
313.362.812.81