Basic Information
ID: ALA3436041
Type: Functional
Description: ST_JUDE_LEISH: Cytotoxicity against transgenic Leishmania Mexicana promastigotes LmGLUT1 that are glucose transport deficient and complemented with the human glucose transporter GLUT1. Activity is measured by DNA content using SYBR green in vitro
Format: BAO_0000019
Organism: Leishmania mexicana
Target: Glucose transporter(ALA2535)
Document: ALA3433997
ST_JUDE_LEISH: Cytotoxicity against transgenic Leishmania Mexicana promastigotes LmGLUT1 that are glucose transport deficient and complemented with the human glucose transporter GLUT1. Activity is measured by DNA content using SYBR green in vitro: 32
Activity Charts
Bioactivity
Activity Types for Assay ALA3436041
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 291.40 | 3.88 | 3.88 |
| 277.80 | 3.64 | 3.64 |
| 368.48 | 4.88 | 4.88 |
| 279.39 | 3.75 | 3.75 |
| 245.28 | 2.68 | 2.68 |
| 325.59 | 4.75 | 4.75 |
| 319.45 | 4.59 | 4.59 |
| 323.35 | 3.09 | 3.09 |
| 636.71 | 10.45 | 10.45 |
| 292.34 | 3.42 | 3.42 |
| 370.49 | 3.80 | 3.80 |
| 447.54 | 6.42 | 6.42 |
| 457.83 | 4.30 | 4.30 |
| 470.17 | 6.64 | 6.64 |
| 356.43 | 4.99 | 4.99 |
| 434.49 | 5.47 | 5.47 |
| 371.87 | 2.83 | 2.83 |
| 298.77 | 5.03 | 5.03 |
| 468.34 | 3.78 | 3.78 |
| 199.25 | 2.98 | 2.98 |
| 326.40 | 4.99 | 4.99 |
| 341.42 | 4.76 | 4.76 |
| 554.51 | 7.90 | 7.90 |
| 328.20 | 2.53 | 2.53 |
| 659.69 | 6.64 | 6.64 |
| 293.32 | 3.78 | 3.78 |
| 345.83 | 2.90 | 2.90 |
| 337.43 | 5.52 | 5.52 |
| 359.43 | 5.61 | 5.61 |
| 346.90 | 3.79 | 3.79 |
| 347.84 | 4.08 | 4.08 |
| 318.33 | 4.39 | 4.39 |
| 382.87 | 2.65 | 2.65 |
| 463.96 | 4.65 | 4.65 |
| 287.79 | 4.31 | 4.31 |
| 335.84 | 3.43 | 3.43 |
| 440.29 | 3.00 | 3.00 |
| 232.71 | 3.49 | 3.49 |
| 371.46 | 5.95 | 5.95 |
| 391.41 | 4.14 | 4.14 |
| 355.44 | 4.97 | 4.97 |
| 420.33 | 6.70 | 6.70 |
| 354.81 | 5.78 | 5.78 |
| 348.40 | 4.67 | 4.67 |
| 356.43 | 5.57 | 5.57 |
| 469.01 | 5.99 | 5.99 |
| 409.51 | 4.62 | 4.62 |
| 357.89 | 4.75 | 4.75 |
| 662.87 | 3.60 | 3.60 |
| 308.36 | 4.28 | 4.28 |
| 320.40 | 4.15 | 4.15 |
| 480.59 | 7.28 | 7.28 |
| 357.25 | 5.45 | 5.45 |
| 420.51 | 3.92 | 3.92 |
| 308.39 | 3.39 | 3.39 |
| 245.32 | 3.60 | 3.60 |
| 279.34 | 3.29 | 3.29 |
| 359.48 | 3.73 | 3.73 |
| 349.22 | 4.08 | 4.08 |
| 621.78 | 7.23 | 7.23 |
| 501.37 | 7.04 | 7.04 |
| 469.31 | 3.61 | 3.61 |
| 305.85 | 3.63 | 3.63 |
| 380.36 | 4.82 | 4.82 |
| 559.64 | 6.40 | 6.40 |
| 448.59 | 5.01 | 5.01 |
| 286.20 | 4.11 | 4.11 |
| 282.16 | 2.54 | 2.54 |
| 366.89 | 3.95 | 3.95 |
| 434.56 | 5.33 | 5.33 |
| 462.62 | 5.40 | 5.40 |
| 414.49 | 4.73 | 4.73 |
| 377.91 | 4.04 | 4.04 |
| 417.44 | 4.96 | 4.96 |
| 468.47 | 5.09 | 5.09 |
| 303.79 | 4.09 | 4.09 |
| 436.01 | 5.10 | 5.10 |
| 391.90 | 4.48 | 4.48 |
| 458.86 | 5.49 | 5.49 |
| 327.43 | 4.18 | 4.18 |
| 363.46 | 4.65 | 4.65 |
| 314.82 | 4.55 | 4.55 |
| 395.53 | 5.20 | 5.20 |
| 425.96 | 4.84 | 4.84 |
| 458.63 | 4.56 | 4.56 |
| 278.71 | 4.43 | 4.43 |
| 400.46 | 4.42 | 4.42 |
| 315.84 | 4.99 | 4.99 |
| 352.79 | 5.61 | 5.61 |
| 425.96 | 4.84 | 4.84 |
| 450.58 | 5.35 | 5.35 |
| 350.85 | 5.53 | 5.53 |
| 416.29 | 4.16 | 4.16 |
| 417.98 | 4.25 | 4.25 |
| 308.43 | 3.69 | 3.69 |
| 297.24 | 2.35 | 2.35 |
| 384.50 | 3.67 | 3.67 |
| 398.46 | 5.24 | 5.24 |
| 403.95 | 3.86 | 3.86 |
| 358.44 | 6.34 | 6.34 |