Assay Report Card

Basic Information

ID: ALA3508969

Type: ADME

Description: Estimated contribution of CYP3A4/5 to oxidative metabolism of [14C] aliskiren hemifumarate based on studies with microsomes from baculovirus-infected insect cells expressing recombinant human CYP450s and studies with pooled human liver microsomes from 22 donors

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsome

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
671.833.293.29