Assay Report Card

Basic Information

ID: ALA3527650

Type: ADME

Description: Activity of human recombinant CYP2C8 expressed in microsomes isolated from human AHH-1 cells assessed as enzyme-mediated 1-(2-(2,4-dimethylphenylsulfinyl)phenyl)piperazine formation at 8 to 50 uM after 120 mins by HPLC/MS-MS analysis in presence of NADPH regenerating system with NADP+

Organism: Homo sapiens

Cell type: AHH-1

Subcellular Fraction: Microsomes

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
379.373.863.86