ID: ALA3527654
Type: ADME
Description: Activity of human recombinant CYP2C9 expressed in microsomes isolated from human AHH-1 cells assessed as enzyme-mediated 4-(2-(2,4-dimethylphenylthio)phenyl)piperazin-1-ol formation at 8 to 50 uM after 120 mins by HPLC/MS-MS analysis in presence of NADPH regenerating system with NADP+
Organism: Homo sapiens
Cell type: AHH-1
Subcellular Fraction: Microsomes
Bioactivity
Activity Types for Assay ALA3527654
Drug metabolism
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
379.37 | 3.86 | 3.86 |