Assay Report Card

Basic Information

ID: ALA3527654

Type: ADME

Description: Activity of human recombinant CYP2C9 expressed in microsomes isolated from human AHH-1 cells assessed as enzyme-mediated 4-(2-(2,4-dimethylphenylthio)phenyl)piperazin-1-ol formation at 8 to 50 uM after 120 mins by HPLC/MS-MS analysis in presence of NADPH regenerating system with NADP+

Organism: Homo sapiens

Cell type: AHH-1

Subcellular Fraction: Microsomes

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
379.373.863.86