Activity of human recombinant CYP2B6 expressed in microsomes isolated from human AHH-1 cells assessed as enzyme-mediated 4-(2-(2,4-dimethylphenylthio)...

ID: ALA3527656

Type: ADME

Description: Activity of human recombinant CYP2B6 expressed in microsomes isolated from human AHH-1 cells assessed as enzyme-mediated 4-(2-(2,4-dimethylphenylthio)phenyl)piperazin-1-ol formation at 8 to 50 uM after 120 mins by HPLC/MS-MS analysis in presence of NADPH regenerating system with NADP+

Format: BAO_0000219

Organism: Homo sapiens

Cell type: AHH-1

Subcellular Fraction: Microsomes

Target:  Cytochrome P450 2B6(ALA4729)

Document:  ALA3525899

Activity of human recombinant CYP2B6 expressed in microsomes isolated from human AHH-1 cells assessed as enzyme-mediated 4-(2-(2,4-dimethylphenylthio)phenyl)piperazin-1-ol formation at 8 to 50 uM after 120 mins by HPLC/MS-MS analysis in presence of NADPH regenerating system with NADP+: 1