Drug uptake ratio assessed as enzyme-mediated uptake in HEK293 cells expressing human OATP1B1 at 1 uM at 37 degC for 3 mins by liquid scintillation sp...

Basic Information

ID: ALA3528696

Type: ADME

Description: Drug uptake ratio assessed as enzyme-mediated uptake in HEK293 cells expressing human OATP1B1 at 1 uM at 37 degC for 3 mins by liquid scintillation spectroscopy relative to wild type

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HEK293

Target:  Solute carrier organic anion transporter family member 1B1(ALA1697668)

Document:  ALA3525928

Drug uptake ratio assessed as enzyme-mediated uptake in HEK293 cells expressing human OATP1B1 at 1 uM at 37 degC for 3 mins by liquid scintillation spectroscopy relative to wild type: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
325.774.324.32
481.552.402.40
350.443.293.29
780.952.222.22