Basic Information
ID: ALA3529280
Type: ADME
Description: Transporter substrate index ratio of permeability from basolateral to apical side in human Caco2 cells at 10 uM up to 120 mins by HPLC-MC analysis in presence of 1 uM of P-gp inhibitor LY335979
Organism: Homo sapiens
Cell type: Caco-2
Activity Charts
Bioactivity
Activity Types for Assay ALA3529280
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.41 | 1.78 | 1.78 |
| 331.35 | 1.58 | 1.58 |
| 319.34 | 1.27 | 1.27 |
| 804.03 | 4.64 | 4.64 |
| 290.32 | 1.26 | 1.26 |
| 454.61 | 5.09 | 5.09 |
| 398.40 | 3.70 | 3.70 |
| 414.53 | 3.37 | 3.37 |
| 407.51 | 4.95 | 4.95 |
| 302.24 | 2.91 | 2.91 |
| 252.35 | 0.60 | 0.60 |
| 328.41 | 2.14 | 2.14 |
| 330.75 | 1.89 | 1.89 |
| 309.33 | 4.44 | 4.44 |
| 375.87 | 4.43 | 4.43 |
| 444.49 | -0.14 | -0.14 |
| 586.69 | 4.09 | 4.09 |
| 319.88 | 4.81 | 4.81 |
| 327.38 | 1.30 | 1.30 |
| 421.45 | 1.85 | 1.85 |
| 853.92 | 3.74 | 3.74 |
| 187.20 | 1.02 | 1.02 |
| 733.94 | 1.79 | 1.79 |
| 306.28 | 0.74 | 0.74 |
| 399.44 | 2.87 | 2.87 |
| 356.42 | 4.37 | 4.37 |
| 670.86 | 3.09 | 3.09 |
| 613.80 | 2.87 | 2.87 |
| 567.80 | 4.75 | 4.75 |
| 505.64 | 2.40 | 2.40 |
| 388.42 | 1.57 | 1.57 |
| 295.41 | 1.32 | 1.32 |
| 336.43 | 2.37 | 2.37 |
| 374.48 | 1.80 | 1.80 |
| 608.69 | 4.17 | 4.17 |
| 404.49 | 3.80 | 3.80 |
| 477.05 | 5.09 | 5.09 |
| 588.56 | 1.34 | 1.34 |
| 810.99 | 3.99 | 3.99 |
| 1202.63 | ||
| 365.84 | 2.71 | 2.71 |
| 480.65 | 4.94 | 4.94 |
| 501.67 | 5.51 | 5.51 |
| 504.64 | -0.02 | -0.02 |
| 720.96 | 5.91 | 5.91 |
| 493.62 | 4.59 | 4.59 |
| 388.90 | 3.15 | 3.15 |
| 435.53 | 4.16 | 4.16 |
| 824.97 | 3.52 | 3.52 |
| 531.44 | 4.21 | 4.21 |
| 527.53 | 1.03 | 1.03 |
| 425.92 | 3.35 | 3.35 |
| 479.53 | 3.68 | 3.68 |
| 1255.44 | ||
| 656.66 | 2.75 | 2.75 |
| 778.95 | 4.75 | 4.75 |
| 747.96 | 2.44 | 2.44 |
| 780.95 | 2.22 | 2.22 |
| 1736.18 | ||
| 411.47 | 4.63 | 4.63 |