Basic Information
ID: ALA3529566
Type: ADME
Description: Activity of human recombinant CYP3A4 assessed as enzyme-mediated 2-hydroxyethyl (1R,3aR,4aR,6R,8aR,9S,9aS)-9-((E)-2-(5-(3-fluorophenyl)pyridin-2-yl)vinyl)-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-ylcarbamate formation at 25 uM after 120 mins by LC-MS/MS analysis in presence of NADPH
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3529566
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 494.58 | 5.63 | 5.63 |