Basic Information
ID: ALA3530293
Type: ADME
Description: Activity of rat recombinant CYP1A1 expressed in baculovirus-infected insect cells assessed as enzyme-mediated N-((4-(4-fluorophenyl)-2-oxochroman-7-yl)methyl)-2-((S)-2-hydroxy-2-(trifluoromethyl)butanoyl)hydrazinecarboxamide formation at 10 uM preincubated for 3 mins measured after 30 mins in presence of 1 mM NADPH
Format: BAO_0000219
Organism: Rattus norvegicus
Target: Cytochrome P450 1A1(ALA2922)
Document: ALA3526019
Activity of rat recombinant CYP1A1 expressed in baculovirus-infected insect cells assessed as enzyme-mediated N-((4-(4-fluorophenyl)-2-oxochroman-7-yl)methyl)-2-((S)-2-hydroxy-2-(trifluoromethyl)butanoyl)hydrazinecarboxamide formation at 10 uM preincubated for 3 mins measured after 30 mins in presence of 1 mM NADPH: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3530293
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 463.39 | 4.75 | 4.75 |