Assay Report Card

Basic Information

ID: ALA3530294

Type: ADME

Description: Activity of rat recombinant CYP1A2 expressed in baculovirus-infected insect cells assessed as enzyme-mediated N-((4-(4-fluorophenyl)-2-oxochroman-7-yl)methyl)-2-((S)-2-hydroxy-2-(trifluoromethyl)butanoyl)hydrazinecarboxamide formation at 10 uM preincubated for 3 mins measured after 30 mins in presence of 1 mM NADPH

Organism: Rattus norvegicus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
463.394.754.75