Inhibition of CYP3A-mediated 1'-OH midazolam formation in human liver microsomes preincubated for 15 mins before substrate addition by LC-MS method

Basic Information

ID: ALA3531038

Type: ADME

Description: Inhibition of CYP3A-mediated 1'-OH midazolam formation in human liver microsomes preincubated for 15 mins before substrate addition by LC-MS method

Format: BAO_0000019

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsomes

Target:  Cytochrome P450 3A(ALA2364675)

Document:  ALA3526092

Inhibition of CYP3A-mediated 1'-OH midazolam formation in human liver microsomes preincubated for 15 mins before substrate addition by LC-MS method: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
804.034.644.64
1202.63