Basic Information
ID: ALA3531251
Type: ADME
Description: Drug metabolism in human liver microsomes assessed as (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-(2-(dimethylamino)ethylamino)-13-hydroxy-10-(hydroxymethyl)-8,14-dimethoxy-4,12,16-trimethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate formation at 1 uM 17-DMAG by liquid chromatography-tandem mass spectrometry in presence of 1 uM ketoconazole CYP3A inhibitor
Organism: Homo sapiens
Tissue: Liver
Activity Charts
Bioactivity
Activity Types for Assay ALA3531251
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 616.76 | 1.91 | 1.91 |
| 632.75 | 0.89 | 0.89 |