Basic Information
ID: ALA3531465
Type: ADME
Description: Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS method
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3531465
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 254.24 | 2.87 | 2.87 |
| 270.24 | 2.58 | 2.58 |
| 176.17 | 1.81 | 1.81 |
| 296.41 | 3.61 | 3.61 |
| 222.37 | 4.40 | 4.40 |
| 406.48 | 3.74 | 3.74 |
| 234.20 | 2.78 | 2.78 |
| 392.41 | 2.35 | 2.35 |
| 240.21 | 1.87 | 1.87 |
| 720.96 | 5.91 | 5.91 |
| 282.22 | 3.54 | 3.54 |
| 144.17 | 2.55 | 2.55 |
| 531.44 | 4.21 | 4.21 |
| 444.42 | 0.91 | 0.91 |
| 776.87 | 4.56 | 4.56 |
| 268.27 | 1.48 | 1.48 |