ID: ALA3531479
Type: ADME
Description: Activity of human recombinant CYP3A4 expressed in insect BTI-TN-5B1-4 cell microsomes assessed as enzyme-mediated drug metabolism treated with (S)-1-pyridin-4-yl-4-fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-3-amine at 2 uM after 30 mins
Format: BAO_0000219
Organism: Homo sapiens
Cell type: BTI-TN-5B1-4
Target: Cytochrome P450 3A4(ALA340)
Document: ALA3526102
Activity of human recombinant CYP3A4 expressed in insect BTI-TN-5B1-4 cell microsomes assessed as enzyme-mediated drug metabolism treated with (S)-1-pyridin-4-yl-4-fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-3-amine at 2 uM after 30 mins: 1
Bioactivity
Activity Types for Assay ALA3531479
Drug metabolism
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
397.41 | 2.93 | 2.93 |