Activity of human recombinant CYP3A4 expressed in insect BTI-TN-5B1-4 cell microsomes assessed as enzyme-mediated drug metabolism treated with (S)-1-p...

Basic Information

ID: ALA3531479

Type: ADME

Description: Activity of human recombinant CYP3A4 expressed in insect BTI-TN-5B1-4 cell microsomes assessed as enzyme-mediated drug metabolism treated with (S)-1-pyridin-4-yl-4-fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-3-amine at 2 uM after 30 mins

Format: BAO_0000219

Organism: Homo sapiens

Cell type: BTI-TN-5B1-4

Target:  Cytochrome P450 3A4(ALA340)

Document:  ALA3526102

Activity of human recombinant CYP3A4 expressed in insect BTI-TN-5B1-4 cell microsomes assessed as enzyme-mediated drug metabolism treated with (S)-1-pyridin-4-yl-4-fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-3-amine at 2 uM after 30 mins: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
397.412.932.93