Basic Information
ID: ALA3531877
Type: ADME
Description: Activation of rat PXR expressed in human HepG2 cells up to 46 uM after 24 hrs by luciferase reporter gene based luminescent analysis
Organism: Rattus norvegicus
Cell type: HepG2
Activity Charts
Bioactivity
Activity Types for Assay ALA3531877
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 441.55 | 4.37 | 4.37 |
| 914.19 | 6.18 | 6.18 |
| 804.03 | 4.64 | 4.64 |
| 333.45 | 3.93 | 3.93 |
| 278.44 | 5.66 | 5.66 |
| 314.47 | 5.74 | 5.74 |
| 336.48 | 4.14 | 4.14 |
| 1297.30 | ||
| 356.06 | 5.86 | 5.86 |
| 273.38 | 3.09 | 3.09 |
| 379.46 | 2.25 | 2.25 |
| 551.63 | 4.20 | 4.20 |
| 382.89 | 4.89 | 4.89 |
| 326.44 | 3.52 | 3.52 |
| 383.47 | 3.02 | 3.02 |
| 415.50 | -0.32 | -0.32 |
| 378.43 | 3.52 | 3.52 |
| 206.33 | 2.79 | 2.79 |
| 361.39 | 4.42 | 4.42 |
| 532.47 | 4.46 | 4.46 |
| 495.75 | 6.88 | 6.88 |
| 822.95 | 4.34 | 4.34 |
| 124.23 | 0.21 | 0.21 |
| 785.89 | 6.16 | 6.16 |
| 776.87 | 4.56 | 4.56 |
| 711.88 | 2.87 | 2.87 |
| 567.06 | 2.27 | 2.27 |
| 214.05 | 3.25 | 3.25 |
| 327.47 | 4.14 | 4.14 |
| 591.72 | 8.05 | 8.05 |
| 276.34 | 1.52 | 1.52 |
| 427.57 | 1.41 | 1.41 |
| 612.78 | 5.84 | 5.84 |
| 394.74 | 3.98 | 3.98 |
| 348.48 | 5.57 | 5.57 |
| 650.98 | 3.95 | 3.95 |
| 254.37 | 4.40 | 4.40 |
| 342.44 | 4.68 | 4.68 |
| 478.89 | -0.44 | -0.44 |
| 458.94 | 4.19 | 4.19 |
| 386.58 | 5.87 | 5.87 |