Basic Information
ID: ALA3531881
Type: ADME
Description: Activation of rat PXR expressed in human HepG2 cells after 24 hrs by luciferase reporter gene based luminescent analysis relative to dexamethasone
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: HepG2
Target: Nuclear receptor subfamily 1 group I member 2(ALA2146315)
Document: ALA3525965
Activation of rat PXR expressed in human HepG2 cells after 24 hrs by luciferase reporter gene based luminescent analysis relative to dexamethasone: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3531881
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 426.56 | 4.13 | 4.13 |
| 575.69 | 5.70 | 5.70 |
| 374.48 | 1.80 | 1.80 |
| 407.64 | 3.54 | 3.54 |
| 299.36 | 3.89 | 3.89 |
| 410.51 | 1.52 | 1.52 |
| 371.43 | 2.95 | 2.95 |
| 507.69 | 4.48 | 4.48 |
| 532.47 | 4.46 | 4.46 |
| 389.97 | 4.66 | 4.66 |
| 384.26 | 3.96 | 3.96 |
| 322.40 | 3.29 | 3.29 |
| 385.38 | 2.46 | 2.46 |
| 196.64 | 0.92 | 0.92 |
| 388.42 | 3.20 | 3.20 |
| 376.47 | 2.78 | 2.78 |
| 446.49 | 3.12 | 3.12 |
| 376.47 | 2.92 | 2.92 |
| 370.53 | 4.50 | 4.50 |
| 276.34 | 1.52 | 1.52 |
| 1085.16 | ||
| 294.40 | 3.77 | 3.77 |
| 227.27 | 2.10 | 2.10 |
| 359.57 | 5.73 | 5.73 |
| 377.53 | 4.36 | 4.36 |
| 286.42 | 5.03 | 5.03 |
| 288.44 | 3.81 | 3.81 |
| 367.35 | 2.87 | 2.87 |
| 213.19 | -0.46 | -0.46 |
| 749.30 | 6.20 | 6.20 |