Activation of rat PXR expressed in rat hepatocytes coexpressing CYP3A4 at 10 uM after 24 hrs by dual luciferase reporter gene assay relative to contro...

Basic Information

ID: ALA3532297

Type: ADME

Description: Activation of rat PXR expressed in rat hepatocytes coexpressing CYP3A4 at 10 uM after 24 hrs by dual luciferase reporter gene assay relative to control

Format: BAO_0000219

Organism: Rattus norvegicus

Cell type: Hepatocyte

Target:  Nuclear receptor subfamily 1 group I member 2(ALA2146315)

Document:  ALA3526076

Activation of rat PXR expressed in rat hepatocytes coexpressing CYP3A4 at 10 uM after 24 hrs by dual luciferase reporter gene assay relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
822.954.344.34
341.504.264.26