Activation of PXR in rat hepatocytes assessed as upregulation of CYP3A23 mRNA expression at 10 uM after 24 hrs by RT-PCR analysis relative to control

Basic Information

ID: ALA3532305

Type: ADME

Description: Activation of PXR in rat hepatocytes assessed as upregulation of CYP3A23 mRNA expression at 10 uM after 24 hrs by RT-PCR analysis relative to control

Format: BAO_0000219

Organism: Rattus norvegicus

Cell type: Hepatocyte

Target: Nuclear receptor subfamily 1 group I member 2(ALA2146315)

Document: ALA3526076

Activation of PXR in rat hepatocytes assessed as upregulation of CYP3A23 mRNA expression at 10 uM after 24 hrs by RT-PCR analysis relative to control: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA3532305

Total(1)

Parent Molecular Weight	ALogP	Polar Surface Area
392.47	1.90	1.90

Parent Molecular Weight

ALogP

Polar Surface Area

392.47

1.90

Activation of PXR in rat hepatocytes assessed as upregulation of CYP3A23 mRNA expression at 10 uM after 24 hrs by RT-PCR analysis relative to control

Basic Information

Activity Charts

Compound Summary