Time dependent inhibition of human CYP3A midazolam 1'-hydroxylase activity assessed as decrease in enzyme activity at 1 uM preincubated for 30 mins by...

Basic Information

ID: ALA3532540

Type: ADME

Description: Time dependent inhibition of human CYP3A midazolam 1'-hydroxylase activity assessed as decrease in enzyme activity at 1 uM preincubated for 30 mins by IC25-shift assay

Format: BAO_0000019

Organism: Homo sapiens

Target:  Cytochrome P450 3A(ALA2364675)

Document:  ALA3526089

Time dependent inhibition of human CYP3A midazolam 1'-hydroxylase activity assessed as decrease in enzyme activity at 1 uM preincubated for 30 mins by IC25-shift assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
456.603.803.80