Basic Information
ID: ALA3532960
Type: ADME
Description: Antagonist activity at rat PXR expressed in human HepG2 cells coexpressing CYP3A4 assessed as inhibition of PCN-induced receptor activation up to 100 uM after 24 hrs by dual luciferase reporter gene assay
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: HepG2
Target: Nuclear receptor subfamily 1 group I member 2(ALA2146315)
Document: ALA3526076
Antagonist activity at rat PXR expressed in human HepG2 cells coexpressing CYP3A4 assessed as inhibition of PCN-induced receptor activation up to 100 uM after 24 hrs by dual luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3532960
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 326.30 | -0.74 | -0.74 |