Basic Information
ID: ALA3533224
Type: ADME
Description: Drug metabolism in human liver microsomes assessed as 1 uM CYP3A inhibitor ketoconazole-mediated inhibition of (4E,6Z,8S,9S,10E,12R,13R,14S,16R)-19-(2-(dimethylamino)-1-hydroxyethylamino)-13-hydroxy-12,16-bis(hydroxymethyl)-8,14-dimethoxy-4,10-dimethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate formation at 1 uM 17-DMAG by liquid chromatography-tandem mass spectrometry
Organism: Homo sapiens
Tissue: Liver
Activity Charts
Bioactivity
Activity Types for Assay ALA3533224
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 616.76 | 1.91 | 1.91 |
| 664.75 | -0.82 | -0.82 |