Basic Information
ID: ALA3534178
Type: ADME
Description: Activity of human recombinant CYP2J2 assessed as enzyme-mediated ((4aR,6R)-9-{2-[(1R,4S)-5-((S)-3-Fluoro-phenyl)-pyridin-2-yl]-vinyl}-1-methyl-3-oxo-dodecahydro-naphtho[2,3-c]furan-6-yl)-carbamic acid(R)-2-hydroxy-ethyl ester formation at 10 uM after 120 mins by LC-MS/MS analysis in presence of astemizole
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3534178
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 492.59 | 5.63 | 5.63 |