Basic Information
ID: ALA3534783
Type: ADME
Description: Decrease in CYP3A activity in rifampin-treated human hepatocytes assessed as 6-betahydroxytestosterone formation using testosterone as substrate at 2.5 uM after 30 mins by LC-MS/MS analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Hepatocyte
Target: Cytochrome P450 3A(ALA2364675)
Document: ALA3526139
Decrease in CYP3A activity in rifampin-treated human hepatocytes assessed as 6-betahydroxytestosterone formation using testosterone as substrate at 2.5 uM after 30 mins by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3534783
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 719.92 | 2.58 | 2.58 |