Basic Information
ID: ALA3535051
Type: ADME
Description: Activity of recombinant human CYP2C8 expressed in microsomes isolated from baculovirus infected insect cell assessed as enzyme-mediated compound formation treated with 2-(1-(((1R)-1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(1,2-dihydroxypropan-2-yl)phenyl)propylthio)methyl)cyclopropyl)acetic acid at 0.02 uM after 30 mins by LC-MS analysis
Organism: Homo sapiens
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA3535051
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 616.18 | 8.01 | 8.01 |