Basic Information
ID: ALA3535256
Type: ADME
Description: Time-dependent inhibition of CYP3A in human liver microsomes assessed as testosterone 6-hydroxylation using testosterone as substrate measured after 25-fold diution by LC-MS/MS analysis in presence of NADPH
Format: BAO_0000019
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Cytochrome P450 3A(ALA2364675)
Document: ALA3526139
Time-dependent inhibition of CYP3A in human liver microsomes assessed as testosterone 6-hydroxylation using testosterone as substrate measured after 25-fold diution by LC-MS/MS analysis in presence of NADPH: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3535256
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 719.92 | 2.58 | 2.58 |