Time-dependent inhibition of CYP3A in human liver microsomes assessed as midazolam 1'-hydroxylation using midazolam as substrate by LC-MS/MS analysis

Basic Information

ID: ALA3535260

Type: ADME

Description: Time-dependent inhibition of CYP3A in human liver microsomes assessed as midazolam 1'-hydroxylation using midazolam as substrate by LC-MS/MS analysis

Format: BAO_0000019

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsomes

Target:  Cytochrome P450 3A(ALA2364675)

Document:  ALA3526139

Time-dependent inhibition of CYP3A in human liver microsomes assessed as midazolam 1'-hydroxylation using midazolam as substrate by LC-MS/MS analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
719.922.582.58