Basic Information
ID: ALA3535477
Type: ADME
Description: Drug level in rat liver microsomes assessed as CYP450-mediated compound formation treated with gambogic acid at 50 uM preincubated for 10 mins followed by NADPH addition measured after 1 hr by LC-DAD-MS/MS analysis
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA3535477
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 646.78 | 6.29 | 6.29 |
| 644.76 | 6.45 | 6.45 |