Basic Information
ID: ALA3535830
Type: ADME
Description: Activity of recombinant human CYP3A4 expressed in microsomes isolated from baculovirus infected insect cell assessed as enzyme-mediated 2-(2-((R)-3-((1-(carboxymethyl)cyclopropyl)methylthio)-3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)propyl)phenyl)-2-hydroxypropanoic acid formation at 0.02 uM after 30 mins by LC-MS analysis
Organism: Homo sapiens
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA3535830
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 602.20 | 7.92 | 7.92 |