Drug metabolism in human hepatic microsomes assessed as CYP2B6-mediated formation of 3-(3-hydroxy-1-{4-[(2-phenyl-1,3-thiazol-4-yl)methoxy]benzyl}-1H-...

ID: ALA3535965

Type: ADME

Description: Drug metabolism in human hepatic microsomes assessed as CYP2B6-mediated formation of 3-(3-hydroxy-1-{4-[(2-phenyl-1,3-thiazol-4-yl)methoxy]benzyl}-1H-pyrazol-4-yl)propanoic acid at 10 uM after 15 mins by HPLC analysis in presence of NADPH

Format: BAO_0000019

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsomes

Target:  Cytochrome P450 2B6(ALA4729)

Document:  ALA3525976

Drug metabolism in human hepatic microsomes assessed as CYP2B6-mediated formation of 3-(3-hydroxy-1-{4-[(2-phenyl-1,3-thiazol-4-yl)methoxy]benzyl}-1H-pyrazol-4-yl)propanoic acid at 10 uM after 15 mins by HPLC analysis in presence of NADPH: 1