Basic Information
ID: ALA3535973
Type: ADME
Description: Drug metabolism in human hepatic microsomes assessed as increase of beta-1-O-acyl glucuronide conjugate of sipoglitazar formation at 10 uM after 30 mins by LC-MS and LC-MS/MS analysis in presence of 300 uM of gemfibrozil, NADPH and UDPGA
Format: BAO_0000019
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Target: ADMET(ALA612558)
Document: ALA3525976
Drug metabolism in human hepatic microsomes assessed as increase of beta-1-O-acyl glucuronide conjugate of sipoglitazar formation at 10 uM after 30 mins by LC-MS and LC-MS/MS analysis in presence of 300 uM of gemfibrozil, NADPH and UDPGA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3535973
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 639.68 | 2.40 | 2.40 |