Assay Report Card

Basic Information

ID: ALA3536195

Type: ADME

Description: Activity of recombinant human CYP2E1 expressed in microsomes isolated from baculovirus infected insect cell assessed as enzyme-mediated 2-(2-((R)-3-((1-(carboxymethyl)cyclopropyl)methylthio)-3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)propyl)phenyl)-2-hydroxypropanoic acid formation at 1 uM after 30 mins by LC-MS analysis

Organism: Homo sapiens

Subcellular Fraction: Microsomes

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
602.207.927.92