Drug metabolism in dog liver microsomes assessed as ER-879123 formation at 10 uM after 60 mins in presence of NADH and FMO1 and FMO3 substrate/inhibit...

Basic Information

ID: ALA3536568

Type: ADME

Description: Drug metabolism in dog liver microsomes assessed as ER-879123 formation at 10 uM after 60 mins in presence of NADH and FMO1 and FMO3 substrate/inhibitor methimazole by LC-MS/MS method

Format: BAO_0000019

Organism: Canis lupus familiaris

Tissue: Liver

Target: Liver microsome(ALA2367369)

Document: ALA3525952

Drug metabolism in dog liver microsomes assessed as ER-879123 formation at 10 uM after 60 mins in presence of NADH and FMO1 and FMO3 substrate/inhibitor methimazole by LC-MS/MS method: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA3536568

Drug metabolism

Total(1)

Parent Molecular Weight	ALogP	Polar Surface Area
347.37	2.86	2.86

Parent Molecular Weight

ALogP

Polar Surface Area

347.37

2.86

Drug metabolism in dog liver microsomes assessed as ER-879123 formation at 10 uM after 60 mins in presence of NADH and FMO1 and FMO3 substrate/inhibit...

Basic Information

Activity Charts

Compound Summary