Basic Information
ID: ALA3536663
Type: ADME
Description: Inhibition of Wistar rat KMO assessed as 3-hydroxykynurenine formation preincubated for 5 mins using 100 uM kynurenine as substrate by LC-MS/MS analysis
Format: BAO_0000357
Organism: Rattus norvegicus
Target: Kynurenine 3-monooxygenase(ALA3457)
Document: ALA3526063
Inhibition of Wistar rat KMO assessed as 3-hydroxykynurenine formation preincubated for 5 mins using 100 uM kynurenine as substrate by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3536663
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 421.46 | 3.54 | 3.54 |
| 518.62 | 4.52 | 4.52 |
| 451.48 | 3.03 | 3.03 |
| 450.50 | 3.00 | 3.00 |